Author

I. Pleines

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Nieswandt· 3 shared C. Kusch· 2 shared I. C. Becker· 2 shared M. Englert· 2 shared T. Heib· 2 shared Z. Nagy· 2 shared A. A. Baig· 1 shared A. Gerber· 1 shared

Activity by Year

2021-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersCell Biology

B. Nieswandt

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

G6b-B regulates an essential step in megakaryocyte maturation

I. C. Becker, Z. Nagy, G. Manukjan, M. Haffner-Luntzer, M. Englert, T. Heib, T. Voegtle, C. Gross, R. Bharti, S. Dietrich, K. Mott, J. Heck, A. Jeschke, T. Schinke, N. Schlegel, , B. Nieswandt

This study identifies G6b-B's critical role in early megakaryocyte differentiation by analyzing a mouse model with a mutation causing macrothrombocytopenia and myelofibrosis.

bioRxiv · Nov 11, 2021Cell Biology

Microthrombocytopenia caused by impaired microtubule stability in RhoB-deficient mice

M. Englert, K. Aurbach, A. Gerber, T. Heib, I. C. Becker, L. M. Wackerbarth, C. Kusch, A. A. Baig, S. Duetting, U. G. Knaus, C. Stigloher, B. Nieswandt, I. Pleines, Z. Nagy

This study shows that RhoB deficiency in mice causes microthrombocytopenia due to impaired microtubule stability, distinct from RhoA's role.

bioRxiv · Nov 4, 2021 · PreprintCell Biology

Loss of Hem1 disrupts macrophage function and impacts on migration, phagocytosis and integrin-mediated adhesion

S. Stahnke, H. Döring, C. Kusch, D. J. J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, , T. E. B. Stradal

This study shows that Hem1 deficiency impairs macrophage migration, phagocytosis, and integrin-mediated adhesion by disrupting WRC function and paxillin phosphorylation.

Current Biology · May 1, 2021Peer-reviewedCell Biology