Author

J. Faix

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Research Focus:development & morphogenesis· 4 Organism:mouse· 3 Research Focus:clustering· 2 Assay:proteomics· 2 Organism:rat· 2

Frequent Co-Authors

K. Rottner· 4 shared G. Dimchev· 2 shared M. Sixt· 2 shared S. Koerber· 2 shared T. E. B. Stradal· 2 shared T. Pokrant· 2 shared A. C. Humphries· 1 shared A. Disanza· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCell Biology

K. Rottner

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5 papers

Recent·Most cited

Convergence of Ras- and Rac-regulated formin pathways is pivotal for phagosome formation and particle uptake in Dictyostelium

S. Koerber, A. Junemann, C. Litschko, M. Winterhoff, J. Faix

This study shows that ForG and ForB formins work together to form actin filaments at the base of phagocytic cups in Dictyostelium, essential for macroendocytosis.

bioRxiv · Jun 21, 2022Cell Biology

Ena/VASP clustering at microspike tips involves Lamellipodin but not I-BAR proteins, and absolutely requires unconventional Myosin-X

T. Pokrant, J. I. Hein, S. Koerber, A. Disanza, A. Pich, G. Scita, K. Rottner, J. Faix

This study identifies unconventional Myosin-X as essential for Ena/VASP clustering and microspike formation, while showing Lamellipodin is involved but inverse BAR-domain proteins are not.

bioRxiv · May 12, 2022Cell Biology

Loss of Hem1 disrupts macrophage function and impacts on migration, phagocytosis and integrin-mediated adhesion

S. Stahnke, H. Döring, C. Kusch, D. J. J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, , T. E. B. Stradal

This study shows that Hem1 deficiency impairs macrophage migration, phagocytosis, and integrin-mediated adhesion by disrupting WRC function and paxillin phosphorylation.

Current Biology · May 1, 2021Peer-reviewedCell Biology

Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation

G. Dimchev, B. Amiri, A. C. Humphries, M. Schaks, V. Dimchev, T. E. B. Stradal, J. Faix, M. Krause, M. Way, M. Falcke, K. Rottner

This study shows that lamellipodin stabilizes protrusions and promotes adhesion formation, enhancing cell migration efficiency.

Journal of Cell Science · Apr 9, 2020Peer-reviewedCell Biology

Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion

J. Damiano-Guercio, L. Kurzawa, J. Mueller, M. Nemethova, G. Dimchev, T. Pokrant, S. Bruehmann, J. Linkner, L. Blanchoin, M. Sixt, K. Rottner, J. Faix

This study shows that Ena/VASP proteins promote cell migration by regulating lamellipodium architecture, actin dynamics, and integrin-dependent adhesion.

bioRxiv · Jan 27, 2020Cell Biology