Author

C. Kusch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

B. Nieswandt· 4 shared I. Pleines· 2 shared M. Englert· 2 shared A. A. Baig· 1 shared A. Elgheznawy· 1 shared A. Gerber· 1 shared A. Guledani· 1 shared A. Steffen· 1 shared

Activity by Year

2021-2021 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersCell Biology

B. Nieswandt

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to G protein-coupled receptor agonists and accelerates thrombus formation in vivo

A. Elgheznawy, P. Oeftering, M. Englert, F. Kaiser, C. Kusch, U. Gbureck, M. R. Boesl, B. Nieswandt, T. Voegtle, H. M. Hermanns

This study shows that loss of ZIP1 and ZIP3 in mice leads to increased platelet reactivity and faster thrombus formation, despite normal Zn2+ levels.

bioRxiv · Nov 19, 2021 · PreprintBiochemistry

Microthrombocytopenia caused by impaired microtubule stability in RhoB-deficient mice

M. Englert, K. Aurbach, A. Gerber, T. Heib, I. C. Becker, L. M. Wackerbarth, C. Kusch, A. A. Baig, S. Duetting, U. G. Knaus, C. Stigloher, B. Nieswandt, I. Pleines, Z. Nagy

This study shows that RhoB deficiency in mice causes microthrombocytopenia due to impaired microtubule stability, distinct from RhoA's role.

bioRxiv · Nov 4, 2021 · PreprintCell Biology

Loss of Hem1 disrupts macrophage function and impacts on migration, phagocytosis and integrin-mediated adhesion

S. Stahnke, H. Döring, C. Kusch, D. J. J. de Gorter, S. Dütting, A. Guledani, I. Pleines, M. Schnoor, M. Sixt, R. Geffers, M. Rohde, M. Müsken, F. Kage, A. Steffen, J. Faix, , T. E. B. Stradal

This study shows that Hem1 deficiency impairs macrophage migration, phagocytosis, and integrin-mediated adhesion by disrupting WRC function and paxillin phosphorylation.

Current Biology · May 1, 2021Peer-reviewedCell Biology

Mapping densely packed GPIIb/IIIa receptors in murine blood platelets with expansion microscopy

H. S. Heil, M. Aigner, S. Maier, P. Gupta, L. M. C. Evers, V. Goeb, C. Kusch, M. Meub, B. Nieswandt, D. Stegner, K. G. Heinze

This paper uses expansion microscopy to study GPIIb/IIIa receptor distribution in murine platelets, revealing clusters in resting platelets that persist through activation.

bioRxiv · Feb 16, 2021 · PreprintBiophysics