Author

I. Reddin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

M. Michaelis· 3 shared M. N. Wass· 2 shared T. R. Fenton· 2 shared A. Chakravarthy· 1 shared A. Feber· 1 shared A. Kelsey· 1 shared A. Nist· 1 shared A. Soleiman· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersPharmacology & Toxicology

M. Michaelis

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Author profile →

4 papers

Recent·Most cited

Combination EZH2 inhibition and retinoic acid treatment promotes differentiation and apoptosis in rhabdomyosarcoma cells

E. OBrien, C. Tse, I. Tracy, I. Reddin, J. Selfe, J. Gibson, W. Tapper, R. J. Pengelly, J. Gao, E. Aladowicz, G. Petts, K. Thway, S. Popov, A. Kelsey, T. J. Underwood, , Z. S. Walters

This study shows that combining EZH2 inhibition with retinoic acid treatment reduces RMS cell proliferation by inducing apoptosis or differentiation depending on the RMS subtype.

bioRxiv · Jun 12, 2023 · PreprintCancer Biology

Data variability in standardised cell culture experiments

I. Reddin, T. R. Fenton, M. N. Wass, M. Michaelis

The paper analyzes variability in drug response data from standardized cell culture experiments and finds high intrinsic variability even among well-controlled experiments.

bioRxiv · Feb 27, 2021 · PreprintPharmacology & Toxicology

Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance.

A. Chakravarthy, I. Reddin, S. Henderson, C. Dong, N. Kirkwood, M. Jeyakumar, D. Rothschild Rodriguez, N. Gonzalez Martinez, J. McDermott, X. Su, N. Egawa, C. S. Fjeldbo, V. E. Skingen, M. K. Halle, C. Krakstad, , T. R. Fenton

The paper identifies two prognostic cervical squamous cell carcinoma subtypes across three continents, revealing conserved molecular and immune features.

bioRxiv · Apr 2, 2020 · PreprintCancer Biology

Drug-adapted cancer cell lines reveal drug-induced heterogeneity and enable the identification of biomarker candidates for the acquired resistance setting

M. Michaelis, M. N. Wass, I. Reddin, Y. Voges, F. Rothweiler, S. Hehlgans, J. Cinatl, M. Mernberger, A. Nist, T. Stiewe, F. Roedel, J. Cinatl

The paper investigates drug-induced heterogeneity in cancer cell lines and identifies biomarkers for acquired resistance to YM155.

bioRxiv · Feb 13, 2020Pharmacology & Toxicology