Author

I. Sharma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Ecology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:Arabidopsis· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Larregina· 1 shared A. V. LEE· 1 shared D. Banerjee· 1 shared D. Boone· 1 shared D. Gau· 1 shared D. L. Galson· 1 shared F. Chen· 1 shared F. J. Nicholls· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

A. Larregina

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Author profile →

4 papers

Recent·Most cited

Wastelands or Preferred-lands? Indicators for redefining Desert conservation

M. Mukherjee, D. Banerjee, I. Sharma, M. Mukerji

This study redefines desert conservation by showing that arid environments support significant biodiversity, using avian and insect data to challenge the wasteland perception.

Journal of Arid Environments · Aug 1, 2025Peer-reviewedEcology

Breast cancer cells promote osteoclast differentiation in an MRTF-dependent paracrine manner

P. Chawla, I. Sharma, D. Gau, I. Eder, F. Chen, V. Yu, N. Welling, D. Boone, J. Taboas, A. V. LEE, A. Larregina, D. L. Galson, P. Roy

This study shows that MRTF in breast cancer cells promotes osteoclast differentiation via paracrine signaling, enhancing bone metastasis, and suggests MRTF inhibition as a potential therapeutic strategy.

bioRxiv · Dec 6, 2023Cancer Biology

Impaired embryo sac cellularization by PMEI gene mutation affects gamete specification and twin plants in Arabidopsis

I. Sharma, P. Malathi, R. Srinivasan, S. R. Bhat, Y. Sreenivasulu

This study shows that PMEI gene mutation in Arabidopsis disrupts embryo sac cellularization, leading to multiple egg cells and twin embryos.

bioRxiv · Oct 17, 2023 · PreprintPlant Biology

LRRK2 is recruited to phagosomes and co-recruits Rab8 and Rab10 in human pluripotent stem cell-derived macrophages

H. Lee, R. Flynn, I. Sharma, P. J. Carling, F. J. Nicholls, M. Stegmann, J. Vowles, R. Wade-Martins, W. S. James, S. A. Cowley

This study shows LRRK2 is recruited to maturing phagosomes and required for Rab8a and Rab10 recruitment in human macrophages.

bioRxiv · Sep 25, 2019Immunology