Author

I. Tolstoy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. B. Prasad· 1 shared A. Gillis· 1 shared A. Isaacs· 1 shared A. M. Kropinski· 1 shared A. Shi· 1 shared B. E. Dutilh· 1 shared C. Hehnly· 1 shared C. Morales· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperMicrobiology

A. B. Prasad

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Author profile →

4 papers

Recent·Most cited

Type IV pili is a critical virulence factor in clinical isolates of Paenibacillus thiaminolyticus

C. Hehnly, A. Shi, P. Ssentongo, L. Zhang, A. Isaacs, S. U. Morton, N. Streck, P. Erdmann-Gilmore, I. Tolstoy, R. R. Townsend, D. D. Limbrick, J. N. Paulson, J. E. Ericson, M. Y. Galperin, S. J. Schiff, J. R. Broach

The paper identifies type IV pili as a critical virulence factor in Paenibacillus thiaminolyticus clinical isolates associated with postinfectious hydrocephalus.

bioRxiv · Jan 24, 2022 · PreprintMicrobiology

Unique genomic features of crAss-like phages, the dominant component of the human gut virome

N. Yutin, S. Benler, S. A. Shmakov, Y. I. Wolf, I. Tolstoy, M. Rayko, D. Antipov, P. A. Pevzner, E. V. Koonin

The paper identifies nearly 600 crAss-like phage genomes from human gut microbiomes, revealing unique genomic features and anti-defense mechanisms.

bioRxiv · Jul 20, 2020 · PreprintMicrobiology

Using the NCBI AMRFinder Tool to Determine Antimicrobial Resistance Genotype-Phenotype Correlations Within a Collection of NARMS Isolates

M. Feldgarden, V. Brover, D. H. Haft, A. B. Prasad, D. J. Slotta, I. Tolstoy, G. H. Tyson, S. Zhao, C.-H. Hsu, P. F. McDermott, D. A. Tadesse, C. Morales, M. Simmons, G. Tillman, J. Wasilenko, , W. Klimke

This paper evaluates AMRFinder, a tool for detecting antimicrobial resistance genes, against phenotypic data from 6,242 isolates, finding high consistency and improved accuracy over previous methods.

bioRxiv · Feb 15, 2019Microbiology

Analysis of Spounaviruses as a Case Study for the Overdue Reclassification of Tailed Bacteriophages

J. Barylski, F. Enault, B. E. Dutilh, M. B. Schuller, R. A. Edwards, A. Gillis, J. Klumpp, P. Knezevic, M. Krupovic, J. H. Kuhn, R. Lavigne, H. M. Oksanen, M. B. Sullivan, J. Wittmann, I. Tolstoy, , E. M. Adriaenssens

The paper evaluates taxonomy methods for bacteriophages using Spounavirinae as a case study, finding they should be divided into at least five subfamilies.

bioRxiv · Feb 7, 2018Microbiology