Author

J. Wittmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 3 Organism:bacteria (other)· 2 Assay:metagenomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

C. Rolland· 2 shared J. Frunzke· 2 shared A. Gillis· 1 shared A. Hardy· 1 shared A. M. Kropinski· 1 shared A. Notaro· 1 shared A. Peschel· 1 shared A. S. Weiss· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersMicrobiology

C. Rolland

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Author profile →

8 papers

Recent·Most cited

Isolation and characterization of the new Streptomyces phages Kamino, Geonosis, Abafar and Scarif infecting a broad range of host species

B. Rackow, C. Rolland, I. Mohnen, J. Wittmann, J. Overmann, J. Frunzke

The paper isolates and characterizes four new Streptomyces phages with varying host ranges and temperate/virulent properties, expanding the available phage resources for studying antiviral strategies in Streptomyces.

bioRxiv · Feb 26, 2024 · PreprintMicrobiology

A rolling circle-replicating plasmid as an Inovirus phage satellite

N. E. Schmid, D. Brandt, C. Walasek, C. Rolland, J. Wittmann, M. Müsken, J. Kalinowski, K. M. Thormann

The paper describes a novel Inovirus phage, Dolos, and its associated rolling circle-replicating plasmid pDolos, which hijacks phage functions to disseminate genetic material.

bioRxiv · Nov 28, 2023 · PreprintMicrobiology

Wall teichoic acid substitution with glucose governs phage susceptibility of Staphylococcus epidermidis

C. R. Beck, J. Krusche, A. Notaro, A. Walter, L. Krankel, A. Vollert, R. Stemmler, J. Wittmann, M. Schaller, C. J. Slavetinsky, C. Mayer, C. De Castro, A. Peschel

This study identifies a WTA glycosyltransferase in S. epidermidis that modifies WTA with glucose, altering phage susceptibility and enabling horizontal gene transfer among CoNS species.

bioRxiv · Jul 27, 2023Microbiology

Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice

A. von Strempel, A. S. Weiss, J. Wittmann, M. Salvado Silva, D. Ring, E. Wortmann, T. Clavel, L. Debarbieux, K. Kleigrewe, B. Stecher

The paper shows that phages targeting protective gut bacteria increase susceptibility to Salmonella Typhimurium infection in gnotobiotic mice.

bioRxiv · Sep 28, 2022 · PreprintMicrobiology

The microRNA processing subunit DGCR8 is required for a T cell-dependent germinal center response

D. Patrick, J. Meinzinger, S. R. Schulz, J. Corte-Real, M. Hauke, E. Roth, W. Schuh, D. Mielenz, J. Wittmann, H.-M. Jäck, K. Pracht

This study shows that DGCR8 is essential for T cell-dependent germinal center responses and antibody production, but not for B-1 cell functions.

bioRxiv · Jul 31, 2022Immunology

A Cytoskeletal Vortex Drives Phage Nucleus Rotation During Jumbo Phage Replication inE. coli

E. A. Birkholz, T. G. Laughlin, S. Suslov, E. Armbruster, J. Lee, J. Wittmann, K. D. Corbett, E. Villa, J. Pogliano

The paper identifies a cytoskeletal vortex in E. coli jumbo phage Goslar that drives phage nucleus rotation, similar to eukaryotic structures.

bioRxiv · Oct 25, 2021Microbiology

Aminoglycoside antibiotics inhibit phage infection by blocking an early step of the phage infection cycle

L. Kever, A. Hardy, T. Luthe, M. Huennefeld, C. Gaetgens, L. Milke, J. Wiechert, J. Wittmann, C. Moraru, J. Marienhagen, J. Frunzke

This study shows aminoglycosides inhibit phage infection by blocking an early step in the viral life cycle, with implications for bacterial community protection.

bioRxiv · May 2, 2021Microbiology

Analysis of Spounaviruses as a Case Study for the Overdue Reclassification of Tailed Bacteriophages

J. Barylski, F. Enault, B. E. Dutilh, M. B. Schuller, R. A. Edwards, A. Gillis, J. Klumpp, P. Knezevic, M. Krupovic, J. H. Kuhn, R. Lavigne, H. M. Oksanen, M. B. Sullivan, J. Wittmann, I. Tolstoy, , E. M. Adriaenssens

The paper evaluates taxonomy methods for bacteriophages using Spounavirinae as a case study, finding they should be divided into at least five subfamilies.

bioRxiv · Feb 7, 2018Microbiology