Author

R. R. Townsend

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Physiology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:proteomics· 4 Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Lesage· 2 shared C. Marionneau· 2 shared D. Maloney· 2 shared J. M. Nerbonne· 2 shared M. Lorenzini· 2 shared P. E. Gilmore· 2 shared R. Sprung· 2 shared S. Burel· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersPhysiology

A. Lesage

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

HTLV-1 infected T cells cause bone loss via small extracellular vesicles

N. K. Pokhrel, A. Panfil, H. Habib, S. Seeniraj, A. Joseph, D. Rauch, R. Sprung, P. E. Gilmore, Q. Zhang, R. R. Townsend, L. Yu, A. S. Yilmaz, R. Aurora, W. Park, L. Ratner, , D. J. Veis

This study shows HTLV-1 infected T cells release small extracellular vesicles that promote bone loss by stimulating osteoclasts, independent of RANKL expression.

Journal of Extracellular Vesicles · Oct 10, 2024Peer-reviewedCancer Biology

Targeted proteomic quantitation of NRF2 signaling and predictive biomarkers in HNSCC

N. Wamsley, E. Wilkerson, L. Guan, K. LaPak, T. Schrank, B. Holmes, R. Sprung, P. E. Gilmore, S. Gerndt, R. Jackson, R. Paniello, P. Pipkorn, S. V. Puram, J. Rich, R. R. Townsend, , M. B. Major

This paper develops a targeted proteomics assay to quantify NRF2 pathway components and clinical biomarkers in HNSCC, identifying correlations between NRF2 activity, HPV infection, and immune markers.

bioRxiv · Mar 13, 2023Cancer Biology

FHF2 phosphorylation and regulation of native myocardial NaV1.5 channels

A. Lesage, M. Lorenzini, S. Burel, M. Sarlandie, F. Bibault, D. Maloney, J. Silva, R. R. Townsend, J. M. Nerbonne, C. Marionneau

This study identifies phosphorylation sites on FHF2 in mouse NaV1.5 channels and shows differential regulation of neonatal and adult ventricular NaV1.5 by FHF2 phosphorylation.

bioRxiv · Jan 31, 2023Physiology

Type IV pili is a critical virulence factor in clinical isolates of Paenibacillus thiaminolyticus

C. Hehnly, A. Shi, P. Ssentongo, L. Zhang, A. Isaacs, S. U. Morton, N. Streck, P. Erdmann-Gilmore, I. Tolstoy, R. R. Townsend, D. D. Limbrick, J. N. Paulson, J. E. Ericson, M. Y. Galperin, S. J. Schiff, J. R. Broach

The paper identifies type IV pili as a critical virulence factor in Paenibacillus thiaminolyticus clinical isolates associated with postinfectious hydrocephalus.

bioRxiv · Jan 24, 2022 · PreprintMicrobiology

Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation reveals multisite regulation of surface expression and gating

M. Lorenzini, S. Burel, A. Lesage, E. Wagner, C. Charriere, P.-M. Chevillard, B. Evrard, D. Maloney, K. M. Ruff, R. V. Pappu, S. Wagner, J. M. Nerbonne, J. R. Silva, R. R. Townsend, L. S. Maier, C. Marionneau

The paper identifies 42 phosphorylation sites on NaV1.5 channels in mouse hearts and shows their roles in regulating channel expression and gating.

bioRxiv · Apr 29, 2020Physiology