Author

I. U. Mysorekar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 3 Assay:proteomics· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

A. M. Salazar· 2 shared B. E. Fashemi· 2 shared C. S. Joshi· 2 shared C. Wang· 2 shared M. M. Ligon· 2 shared A. K. Rougeau· 1 shared A. Kumar· 1 shared A. Mora· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

A. M. Salazar

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Author profile →

5 papers

Recent·Most cited

A new role for IFRD1 in regulation of ER stress in bladder epithelial homeostasis

B. E. Fashemi, A. K. Rougeau, A. M. Salazar, S. J. Bark, R. Chappidi, J. W. Brown, C. J. Cho, J. C. Mills, I. U. Mysorekar

This study identifies IFRD1 as a key regulator of ER stress and urothelial homeostasis in mice, showing its role in maintaining bladder function and preventing cell shedding.

bioRxiv · Jan 9, 2024 · PreprintCell Biology

Discovery And Characterization of Small Molecule Inhibitors of Zika Virus Replication

A. Kumar, D. Kumar, P. Kumar, B. L. Jones, I. U. Mysorekar, R. Giri

This study identifies compound F1289-0194 as a potential inhibitor of Zika virus replication through molecular docking, dynamics simulations, and in vitro testing.

bioRxiv · Dec 15, 2022 · PreprintCell Biology

D-mannose ameliorates age-associated cellular senescence in the bladder urothelium and NLRP3/Gasdermin/IL-1β -driven pyroptotic epithelial cell shedding

C. S. Joshi, A. M. Salazar, C. Wang, M. M. Ligon, R. R. Chappidi, B. E. Fashemi, P. A. Felder, A. Mora, S. L. Grimm, C. Coarfa, I. U. Mysorekar

This study shows that D-mannose reduces age-related bladder urothelial senescence and pyroptotic cell shedding in mice by improving autophagy and reversing SASP.

bioRxiv · Sep 6, 2022Cell Biology

Tertiary lymphoid tissue develops during normal aging in mice and humans

M. M. Ligon, C. Wang, Z. Jennings, C. Schulz, E. N. DeJong, J. L. Lowder, D. M. E. Bowdish, I. U. Mysorekar

This study identifies bladder tertiary lymphoid tissue (bTLT) formation in aged mice and humans, driven by TNF and linked to age-related bladder inflammation.

bioRxiv · Aug 29, 2019 · PreprintImmunology

Functional characterization of Ralstonia insidiosa, a bona fide resident at the maternal-fetal interface

L. A. Parnell, G. G. Willsey, C. S. Joshi, Y. Yin, M. J. Wargo, I. U. Mysorekar

This study characterizes Ralstonia insidiosa as a non-pathogenic resident of the human placental basal plate, showing its localization, replication, and lack of harmful effects.

bioRxiv · Aug 1, 2019 · PreprintMicrobiology