Author

J. C. Mills

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. J. Cho· 2 shared J. W. Brown· 2 shared A. Alarcon de la Lastra· 1 shared A. C. Neininger· 1 shared A. K. Rougeau· 1 shared A. L. Means· 1 shared A. M. Salazar· 1 shared B. Chen· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

C. J. Cho

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A new role for IFRD1 in regulation of ER stress in bladder epithelial homeostasis

B. E. Fashemi, A. K. Rougeau, A. M. Salazar, S. J. Bark, R. Chappidi, J. W. Brown, C. J. Cho, J. C. Mills, I. U. Mysorekar

This study identifies IFRD1 as a key regulator of ER stress and urothelial homeostasis in mice, showing its role in maintaining bladder function and preventing cell shedding.

bioRxiv · Jan 9, 2024 · PreprintCell Biology

Host Gastric Corpus Microenvironment Facilitates Ascaris Suum Larval Hatching And Infection in a Murine Model

Y. WU, G. ADENIYI-IPADEOLA, M. ADKINS-THREATS, M. SEASOCK, C. SUAREZ-REYES, F. RICARDO, M. E. BOTTAZZI, L. SONG, J. C. MILLS, J. E. Weatherhead

This study shows that Ascaris suum larvae hatch in the host stomach, not the small intestine, using gastric acid and AMCase, and demonstrates that inhibiting these factors reduces parasitic burden and lung disease.

bioRxiv · Jun 9, 2023 · PreprintMicrobiology

Pancreas resident macrophage-induced fibrosis has divergent roles in pancreas inflammatory injury and PDAC

J. M. Baer, C. Zuo, L.-I. Kang, A. Alarcon de la Lastra, N. C. Borcherding, B. L. Knolhoff, S. J. Bogner, Y. Zhu, M. A. Lewis, N. Zhang, K.-w. Kim, R. C. Fields, J. C. Mills, L. Ding, G. J. Randolph, D. G. DeNardo

This study shows that pancreas resident macrophages (TRMs) have distinct roles in pancreatitis and pancreatic cancer, promoting fibrosis in inflammation but driving cancer progression.

bioRxiv · Feb 9, 2022 · PreprintImmunology

Single-cell transcriptomics reveals a conserved metaplasia program in pancreatic injury

Z. Ma, N. K. Lytle, B. Chen, N. Jyotsana, S. Weiser Novak, C. J. Cho, L. Caplan, O. Ben-Levy, A. C. Neininger, D. T. Burnette, V. Q. Trinh, M. C. B. Tan, E. A. Patterson, R. Arrojo e Drigo, R. R. Giraddi, , K. E. DelGiorno

The paper uses single-cell RNA sequencing to identify a conserved metaplasia program in pancreatic injury, revealing mucin/ductal populations and neoplastic transformation potential.

bioRxiv · Apr 9, 2021Cell Biology

3'-Sulfated Lewis A is a Biomarker for Metaplastic and Oncogenic Transformation of Several Gastrointestinal Epithelia

J. W. Brown, K. K. Das, V. Kalas, K. Das, J. C. Mills

This study identifies 3-Sulfo-Lewis A as the epitope recognized by the antibody Das-1, which is reexpressed in metaplastic and carcinomatous gastrointestinal lesions.

bioRxiv · Mar 17, 2021 · PreprintCancer Biology