Author

I. Wicks

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Jacobsen· 2 shared A. L. Samson· 2 shared C. Hall· 2 shared J. Hildebrand· 2 shared J. M. Murphy· 2 shared J. Silke· 2 shared K. R. Martin· 2 shared S. Chiou· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

A. Jacobsen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

An immunohistochemical atlas of necroptotic pathway expression

S. Chiou, A. Al-Ani, Y. Pan, K. Patel, I. Kong, L. Whitehead, A. Light, S. Young, M. Barrios, C. Sargeant, P. Rajasekhar, L. Zhu, A. Hempel, A. Lin, J. Rickard, , A. L. Samson

The paper develops automated immunohistochemistry protocols to detect necroptotic pathway proteins in mouse and human tissues, revealing heterogeneity and disease-related changes in expression.

bioRxiv · Oct 31, 2023Cell Biology

A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation

S. E. Garnish, K. R. Martin, M. Kauppi, V. Jackson, R. Ambrose, V. V. Eng, S. Chiou, Y. Meng, D. Frank, E. C. Tovey Crutchfield, K. M. Patel, A. Jacobsen, G. Atkin-Smith, L. Di Rago, M. Doerflinger, , J. Hildebrand

The paper shows that a common MLKL polymorphism, S132P, enhances necroptotic activity in human cells and impairs recovery from infection in mice.

bioRxiv · Sep 8, 2022 · PreprintImmunology

SIDT2 RNA transporter promotes lung and gastrointestinal tumor development

T. Nguyen, K. Bieging-Rolett, T. Putoczki, I. Wicks, L. Attardi, K. Pang

The paper shows that SIDT2 promotes tumor development in lung and gastrointestinal cancers by facilitating RNautophagy, as evidenced by reduced tumor formation in Sidt2-/- mice with oncogenic KrasG12D or Apcmin/+ mutations.

bioRxiv · Aug 9, 2019Cancer Biology