Author

Isara Laothamatas

Howard Hughes Medical Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Assay:proteomics· 1

Frequent Co-Authors

Joseph S. TakahashiiD· 2 shared Carla B. GreeniD· 1 shared Congrong Ye· 1 shared Emil SjulstokiD· 1 shared Jeffrey G. McDonaldiD· 1 shared Kevin M. DeaniD· 1 shared Lauren G. ZachariasiD· 1 shared Lauren PalluthiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersPhysiology

Joseph S. TakahashiORCID

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2 papers

Recent·Most cited

Nocturnin drives mitochondrial NADP(H)/NAD(H) rhythms to regulate steroid rhythm amplitude and time metabolism

Lauren Palluth, Isara Laothamatas, Tammy-Nhu Nguyen, Emil Sjulstok, Lauren G. Zacharias, Mauricio J. Velasquez, Melissa R. Iñigo, Xiaorong Fu, Thomas P. Mathews, Jeffrey G. McDonald, Shawn C. Burgess, Joseph S. Takahashi, Carla B. Green

This study shows that Nocturnin regulates mitochondrial NADP(H)/NAD(H) rhythms, affecting steroid rhythm amplitude and hepatic metabolism in mice.

bioRxiv · Jul 28, 2026 · PreprintPhysiology

Mammalian circadian clock proteins form dynamic interacting microbodies distinct from phase separation

Pancheng Xie, Xiaowen Xie, Congrong Ye, Kevin M. Dean, Isara Laothamatas, S. K. Tahajjul Taufique, Joseph S. Takahashi, Shin Yamazaki, Ying Xu, Yi Liu

The paper shows that endogenous circadian clock proteins form dynamic microbodies distinct from phase separation condensates, suggesting an enzyme-like mechanism in the circadian feedback loop.

Proceedings of the National Academy of Sciences · Dec 21, 2023Peer-reviewedGenetics