Xiaorong Fu

This study shows that Nocturnin regulates mitochondrial NADP(H)/NAD(H) rhythms, affecting steroid rhythm amplitude and hepatic metabolism in mice.

This study shows that excessive fatty acid oxidation in mice leads to heart failure through cardiolipin loss and mitochondrial dysfunction, suggesting that increasing FAO may be harmful in heart failure.

The paper identifies a hepatic lipogenic metabolon that enhances fatty acid and triglyceride synthesis through post-translational regulation, suggesting it as a therapeutic target for metabolic liver diseases.

The paper shows aerobic capacity and exercise enhance bile acid metabolism, which is critical for reducing hepatic steatosis in mice.

This paper develops a mouse model of ECHS1 deficiency and identifies valine metabolism and inflammation as drivers of epilepsy in the disease.