Author

Jörg Drenkow

Cold Spring Harbor Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 4 Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 6 Assay:bulk RNA-seq· 4 Organism:human· 3 Research Focus:benchmarking· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

Alexander DobiniD· 5 shared T GingerasiD· 5 shared Carrie Davis· 4 shared Chris Zaleski· 3 shared Alessandra BreschiiD· 2 shared Alexandra Scavelli· 2 shared Ali MortazaviiD· 2 shared Anna V VlasovaiD· 2 shared

Activity by Year

2012-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersGenomics

Alexander DobinORCID

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Author profile →

6 papers

Recent·Most cited

The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models

Joel S. Rozowsky, Jiahao Gao, Beatrice Borsari, Yucheng Yang, Timur R. Galeev, Gamze Gürsoy, Charles B. Epstein, Kun Xiong, Jinrui Xu, Tianxiao Li, Jason J. Liu, Keyang Yu, Ana Berthel, Zhanlin Chen, Fábio C. P. Navarro, , B Bernstein

The paper introduces the EN-TEx resource, which provides personal epigenomes and variant-impact models across multiple tissues, revealing allele-specific loci and their associations with GWAS loci.

Cell · Mar 1, 2023Peer-reviewedGenomics

Pan-genome Analysis in Sorghum Highlights the Extent of Genomic Variation and Sugarcane Aphid Resistance Genes

Bo Wang, Yinping Jiao, Kapeel M. Chougule, Andrew J. Olson, Jian Huang, Víctor Llaca, Kevin A. Fengler, Xuehong Wei, Liya Wang, Xiao‐Fei Wang, Michael Regulski, Jörg Drenkow, T Gingeras, Chad M. Hayes, John Scott Armstrong, , Doreen Ware

This study constructs high-quality sorghum genome assemblies and identifies structural variations and resistance genes associated with sugarcane aphid resistance.

bioRxiv · Jan 3, 2021 · PreprintGenomics

A limited set of transcriptional programs define major cell types

Alessandra Breschi, Manuel Muñoz-Aguirre, Valentin Wucher, Carrie Davis, Diego Garrido-Martín, Sarah Djebali, Jesse A Gillis, Dmitri Davidovich Pervouchine, Anna V Vlasova, Alexander Dobin, Chris Zaleski, Jörg Drenkow, Cassidy Danyko, Alexandra Scavelli, Ferrán Reverter, , Roderic Guigó

The paper identifies five major cell types based on transcriptional programs in human tissues and shows their composition correlates with tissue morphology and disease.

Genome Research · Jul 1, 2020Peer-reviewedGenomics

Management, Analyses, and Distribution of the MaizeCODE Data on the Cloud

Liya Wang, Zhenyuan Lu, Melissa delaBastide, Peter Van Buren, Xiaofei Wang, Cornel Ghiban, Michael Regulski, Jörg Drenkow, Xiaosa Xu, Carlos Ortiz‐Ramírez, Cristina Fernandez Marco, Sara Goodwin, Alexander Dobin, Kenneth D. Birnbaum, David P. Jackson, , T Gingeras

The paper describes the development of a cloud-based platform for managing, analyzing, and distributing MaizeCODE data, enhancing reproducibility and accessibility.

Frontiers in Plant Science · Mar 31, 2020Peer-reviewedBioinformatics

Dynamics of microRNA expression during mouse prenatal development

Sorena Rahmanian, Rabi Murad, Alessandra Breschi, Weihua Zeng, Mark Mackiewicz, Brian A. Williams, Carrie Davis, Brian S. Roberts, Sarah Kristen Meadows, Dianna E. Moore, Diane E. Trout, Chris Zaleski, Alexander Dobin, Lei-Hoon Sei, Jörg Drenkow, , Ali Mortazavi

The paper analyzes miRNA expression dynamics across mouse embryonic development, identifying tissue-specific clusters and their regulatory roles.

Genome Research · Nov 1, 2019Peer-reviewedGenomics

STAR: ultrafast universal RNA-seq aligner

Alexander Dobin, Carrie Davis, Felix J. Schlesinger, Jörg Drenkow, Chris Zaleski, Sonali Jha, Philippe J. Batut, Mark Chaisson, T Gingeras

Maximum mappable seed search in uncompressed suffix arrays, then seed clustering and stitching, aligns 550 million paired-end reads per hour on 12 cores with better sensitivity and precision.

Bioinformatics · Oct 25, 2012Peer-reviewedBioinformatics