Author

J. A. Levi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. C. Puhl· 2 shared B. L. Hurst· 2 shared B. Yount· 2 shared E. J. Fritch· 2 shared F. Scholle· 2 shared K. H. Pearce· 2 shared L. Premkumar· 2 shared N. J. Johnson· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. C. Puhl

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Characterization and optimization of variability in a human colonic epithelium culture model

C. M. Pike, B. Zwarycz, B. E. McQueen, M. Castillo, C. Barron, J. M. Morowitz, J. A. Levi, D. Phadke, M. Balik-Meisner, D. Mav, R. Shah, D. L. Cunningham Glasspoole, R. Laetham, W. Thelin, M. K. Bunger, E. M. Boazak

The paper characterizes and reduces variability in a human colonic epithelium culture model to improve its predictive value for drug responses.

bioRxiv · Sep 22, 2023 · PreprintCell Biology

Vandetanib Reduces Inflammatory Cytokines and Ameliorates COVID-19 in Infected Mice

A. C. Puhl, G. F. Gomes, S. Damasceno, E. J. Fritch, J. A. Levi, N. J. Johnson, F. Scholle, L. Premkumar, B. L. Hurst, F. LeeMontiel, F. P. Veras, S. S. Batah, A. T. Fabro, N. J. Moorman, B. Yount, , S. Ekins

This study tests FDA-approved kinase inhibitors against SARS-CoV-2 in vitro and in vivo, finding that vandetanib reduces inflammatory cytokines and mitigates lung inflammation in infected mice without reducing viral load.

bioRxiv · Dec 16, 2021 · PreprintImmunology

Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms

A. C. Puhl, E. J. Fritch, T. R. Lane, L. V. Tse, B. Yount, C. Q. Sacramento, T. A. Tavella, F. T. M. Costa, S. Weston, J. Logue, M. Frieman, L. Premkumar, K. H. Pearce, B. L. Hurst, C. H. Andrade, , S. Ekins

This study evaluates the in vitro antiviral activity of three Ebola and Marburg virus inhibitors against SARS-CoV-2 and explores their potential mechanisms of action.

bioRxiv · Dec 1, 2020Pharmacology & Toxicology