Author

K. J. Basham

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1

Frequent Co-Authors

G. D. Hammer· 2 shared K. Converso-Baran· 2 shared T. J. Giordano· 2 shared A. J. Crossen· 1 shared A. M. Lerario· 1 shared B. K. Lohman· 1 shared C. Gonzalez del Rey· 1 shared C. J. Stubben· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

G. D. Hammer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing

J. L. Reedy, K. N. Jensen, A. J. Crossen, K. J. Basham, R. A. Ward, C. M. Reardon, H. B. Harding, O. W. Hepworth, P. Simaku, G. N. Kwaku, K. Tone, J. A. Willment, D. M. Reid, M. H. Stappers, G. D. Brown, , J. M. Vyas

This study shows fungal melanin blocks chemokine secretion and calcium fluxing in airway epithelial cells, reducing neutrophil recruitment to the airway.

bioRxiv · Mar 28, 2023 · PreprintImmunology

Targeting oncogenic Wnt/β-catenin signaling in adrenocortical carcinoma disrupts ECM expression and impairs tumor growth.

M. K. Penny, A. M. Lerario, K. J. Basham, S. Chukkapalli, Y. Yu, D. R. Mohan, C. LaPensee, K. Converso-Baran, M. Hoenerhoff, L. Suarez Fernandez, C. Gonzalez del Rey, T. J. Giordano, R. Han, E. A. Newman, G. D. Hammer

This paper identifies a Wnt/β-catenin-regulated extracellular matrix (ECM) program in adrenocortical carcinoma (ACC) that promotes tumor growth and shows that inhibiting this pathway reduces tumor viability and growth in preclinical models.

bioRxiv · Oct 23, 2022Cancer Biology

Senescence-Induced Immune Remodeling Facilitates Metastatic Adrenal Cancer in a Sex-Dimorphic Manner

K. M. Warde, L. Liu, L. J. Smith, B. K. Lohman, C. J. Stubben, H. A. Ekiz, J. L. Ammer, K. Converso-Baran, T. J. Giordano, G. D. Hammer, K. J. Basham

This study shows that cellular senescence induced by ZNRF3 loss remodels the microenvironment, promoting metastatic adrenal cancer with sex-specific immune responses.

bioRxiv · Apr 29, 2022Cancer Biology