Author

J. L. Reedy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. J. Crossen· 3 shared J. M. Vyas· 3 shared J. Rajagopal· 2 shared R. A. Ward· 2 shared A. Xu· 1 shared B. Lin· 1 shared B. S. Klein· 1 shared C. M. Reardon· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

A. J. Crossen

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Author profile →

3 papers

Recent·Most cited

Single Cell Transcriptomes, Lineage, and Differentiation of Functional Airway Microfold Cells

M. V. Surve, B. Lin, J. L. Reedy, A. J. Crossen, A. Xu, B. S. Klein, J. M. Vyas, J. Rajagopal

This study identifies and characterizes airway Microfold (M) cells using single-cell transcriptomics, revealing their lineage, differentiation pathways, and functional role in antigen sampling via CR2-dependent endocytosis.

bioRxiv · Aug 6, 2023Cell Biology

Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing

J. L. Reedy, K. N. Jensen, A. J. Crossen, K. J. Basham, R. A. Ward, C. M. Reardon, H. B. Harding, O. W. Hepworth, P. Simaku, G. N. Kwaku, K. Tone, J. A. Willment, D. M. Reid, M. H. Stappers, G. D. Brown, , J. M. Vyas

This study shows fungal melanin blocks chemokine secretion and calcium fluxing in airway epithelial cells, reducing neutrophil recruitment to the airway.

bioRxiv · Mar 28, 2023 · PreprintImmunology

The C-type Lectin Receptor Dectin-2 is a receptor for Aspergillus fumigatus galactomannan

J. L. Reedy, A. J. Crossen, P. E. Negoro, H. E. Brown, R. A. Ward, D. A. V. Blanco, K. D. Timmer, M. K. Mansour, M. Wüthrich, T. Fontaine, J.-P. Latgé, J. M. Vyas

This study identifies Dectin-2 as a receptor for Aspergillus fumigatus galactomannan, showing it mediates pro-inflammatory signaling and immune responses.

bioRxiv · Apr 12, 2022Immunology