Author

J. Alba

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:yeast· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

S. Vanni· 2 shared A. A. Teleman· 1 shared A. Desfosses· 1 shared A. Lamprakis· 1 shared A. Roux· 1 shared C. De Virgilio· 1 shared C. Demetriades· 1 shared E. Recio-Fernandez· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiophysics

S. Vanni

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

CryoEM architecture of a native stretch-sensitive membrane microdomain

J. M. Kefauver, M. Hakala, L. Zou, J. Alba, J. Espadas Moreno, M. G. Tettamanti, L. F. Estrozi, S. Vanni, A. Roux, A. Desfosses, R. Loewith

This study determines the cryo-EM structure of native yeast eisosomes, revealing lipid organization and dynamic stretching mechanisms in membrane microdomains.

bioRxiv · Aug 25, 2023Biophysics

Impact of HIV infection and integrase strand transfer inhibitors-based treatment on gut virome

P. Villoslada-Blanco, P. Perez-Matute, M. Iniguez, E. Recio-Fernandez, J. Daan, L. De Coninck, L. Close, P. Blanco-Navarrete, L. Metola, V. Ibarra, J. Alba, J. Matthijnssens, J. A. Oteo

This study evaluates the impact of HIV infection and INSTIs-based treatment on gut virome composition, finding that INSTIs partially restore gut dysbiosis at both bacterial and viral levels.

Scientific Reports · Dec 15, 2022Peer-reviewedMicrobiology

Malonyl-CoA is an ancient physiological ATP-competitive mTORC1 inhibitor

R. Nicastro, L. Brohee, J. Alba, J. Nuechel, G. Figlia, S. Kipschull, P. Gollwitzer, J. Romero-Pozuelo, S. A. Fernandes, A. Lamprakis, S. Vanni, A. A. Teleman, C. De Virgilio, C. Demetriades

The paper shows malonyl-CoA inhibits mTORC1 by competing with ATP, linking lipid biosynthesis to cellular growth regulation in yeast and mammals.

bioRxiv · Nov 6, 2022 · PreprintCell Biology

The full model of the pMHC-TCR-CD3 complex: a structural and kinetics characterization

J. Alba, O. Acuto, M. D'Abramo

The paper presents the first full model of the pMHC-TCR-CD3 complex, revealing conformational changes and signal propagation mechanisms through molecular dynamics simulations.

bioRxiv · Nov 26, 2020 · PreprintImmunology