Author

L. Close

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Organism:rat· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

J. Matthijnssens· 2 shared B. Schepens· 1 shared B. Vanmechelen· 1 shared C. De Keyzer· 1 shared D. De Vlieger· 1 shared D. Jochmans· 1 shared D. Schols· 1 shared D. Van Looveren· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMicrobiology

J. Matthijnssens

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Impact of HIV infection and integrase strand transfer inhibitors-based treatment on gut virome

P. Villoslada-Blanco, P. Perez-Matute, M. Iniguez, E. Recio-Fernandez, J. Daan, L. De Coninck, L. Close, P. Blanco-Navarrete, L. Metola, V. Ibarra, J. Alba, J. Matthijnssens, J. A. Oteo

This study evaluates the impact of HIV infection and INSTIs-based treatment on gut virome composition, finding that INSTIs partially restore gut dysbiosis at both bacterial and viral levels.

Scientific Reports · Dec 15, 2022Peer-reviewedMicrobiology

STAT2 signaling as double-edged sword restricting viral dissemination but driving severe pneumonia in SARS-CoV-2 infected hamsters

R. Boudewijns, H. J. Thibaut, S. J. F. Kaptein, R. Li, V. Vergote, L. Seldeslachts, C. De Keyzer, L. Bervoets, S. Sharma, J. Van Weyenbergh, L. Liesenborghs, J. Ma, S. Jansen, D. Van Looveren, T. Vercruysse, , X. Saelens

This study shows that STAT2 signaling both restricts SARS-CoV-2 spread and causes severe pneumonia in infected hamsters.

bioRxiv · Apr 23, 2020 · PreprintMicrobiology