Author

J. Barnholtz-Sloan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

J. Lathia· 2 shared A. Cohen-Gadol· 1 shared A. Gao· 1 shared A. Lauko· 1 shared A. Rabljenovic· 1 shared A. Steffens· 1 shared A. Zalavadia· 1 shared B. Otvos· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

J. Lathia

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3 papers

Recent·Most cited

Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas

J. Z. Wang, V. Patil, J. Liu, H. Dogan, F. Behling, M. Skardelly, M. Tatagiba, E. Hoffman, S. Bunda, R. Yakubov, R. Kaloti, S. Brandner, A. Gao, A. Cohen-Gadol, J. Barnholtz-Sloan, , International Consortium on Meningiomas (ICOM)

This study investigates the relationship between CDKN2A mRNA expression and clinical outcomes in meningiomas, finding that high expression is associated with poorer progression-free survival and more aggressive tumor characteristics.

Acta Neuropathologica · Jul 1, 2023Peer-reviewedCancer Biology

The MIF SNP rs755622 is a germline determinant of tumor immune activation in Glioblastoma

T. Alban, M. M. Grabowski, B. Otvos, D. B. Watson, A. Zalavadia, V. Makarav, K. M. Troike, M. McGraw, A. Rabljenovic, A. Lauko, C. K. A. Neumann, G. Roversi, K. Waite, G. Cioffi, N. Patil, , J. Lathia

The paper identifies a germline SNP, rs755622, associated with increased leukocyte infiltration in glioblastoma and links it to lactotransferrin expression as a potential biomarker for immune activation.

bioRxiv · Mar 7, 2022 · PreprintCancer Biology

JAM-A functions as a female microglial tumor suppressor in glioblastoma

S. M. Turaga, D. J. Silver, D. Bayik, E. Paouri, S. Peng, N. Borjini, S. Stanko, U. Naik, R. A. Keri, J. R. Connor, J. Barnholtz-Sloan, J. B. Rubin, M. Berens, D. Davalos, J. Lathia

This study shows that JAM-A deficiency in female mice increases microglia activation and GBM growth, revealing a sex-specific role for JAM-A in the tumor microenvironment.

bioRxiv · Sep 11, 2019Cancer Biology