Template-free prediction of a new monotopic membrane protein fold and oligomeric assembly by Alphafold2
A. Gulsevin, B. Han, J. C. Porta, H. Mchaourab, J. Meiler, A. K. Kenworthy
This study uses AlphaFold2 to predict the structure of caveolin-1, revealing its new fold and oligomeric assembly, but notes limitations in predicting higher-order complexes.
bioRxiv · Jul 12, 2022Biophysics