Author

J. Cyrta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:whole-exome sequencing· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Rodriguez· 2 shared A. Sboner· 2 shared D. Prandi· 2 shared H. Beltran· 2 shared M. Rubin· 2 shared S. Piscuoglio· 2 shared S. Tomlins· 2 shared A. Arora· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

A. Rodriguez

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Harbingers of Aggressive Prostate Cancer: Precision Oncology Case Studies

J. Cyrta, D. Prandi, A. Arora, D. H. Hovelson, A. Sboner, A. Rodriguez, T. Fedrizzi, H. Beltran, D. R. Robinson, A. Gopalan, L. True, P. Nelson, B. D. Robinson, J. M. Mosquera, S. Tomlins, , M. Rubin

This study identifies molecular features of primary prostate cancer and their relation to metastasis using genomic and histopathological analysis.

bioRxiv · Nov 30, 2021 · PreprintCancer Biology

Role of Specialized mSWI/SNF Complexes in Prostate Cancer Lineage Plasticity

J. Cyrta, A. Augspach, M. R. de Filippo, D. Prandi, P. Thienger, M. Benelli, V. Cooley, R. Bareja, D. Wilkes, S.-S. Chae, P. Cavaliere, N. Dephoure, A.-C. Uldry, S. B. Lagache, S. Cohen, , M. Rubin

The paper investigates the role of mSWI/SNF complexes in NEPC lineage plasticity using patient data and cell models, finding deregulated subunits and SMARCA4 overexpression linked to aggressive disease.

Nature Communications · Nov 3, 2020Peer-reviewedCancer Biology

The Genomic Landscape of Prostate Cancer Brain Metastases

A. Rodriguez, J. Gallon, D. Akhoundova, S. Maletti, A. Ferguson, J. Cyrta, U. Amstutz, A. Garofoli, V. Paradiso, S. Tomlins, E. Hewer, V. Genitsch, A. Fleischmann, E. J. Rushing, R. Grobholz, , M. A. Rubin

This study identifies genomic alterations in prostate cancer brain metastases, highlighting mutations in NF1 and RICTOR and DNA homologous repair defects as potential drivers.

bioRxiv · May 12, 2020 · PreprintCancer Biology