Author

J. D. D. Klein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

T. A. Rando· 2 shared A. Colville· 1 shared A. d. Morree· 1 shared A. Goshayeshi· 1 shared C. W. Nutter· 1 shared D. I. Benjamin· 1 shared D. K. Nomura· 1 shared D. W. Morgens· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

T. A. Rando

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Author profile →

2 papers

Recent·Most cited

Death-seq identifies regulators of cell death and senolytic therapies

A. Colville, J.-Y. Liu, S. Thomas, H. D. Ishak, R. Zhou, J. D. D. Klein, D. W. Morgens, A. Goshayeshi, J. S. Salvi, D. Yao, K. Spees, M. C. Bassik, T. A. Rando

Death-seq identifies enhancers of cell death and senolytic therapies through a CRISPR screen, revealing synergistic combinations that clear senescent cells without thrombocytopenia.

bioRxiv · Apr 1, 2022Cell Biology

Fasting Induces a Highly Resilient Deep Quiescent State in Muscle Stem Cells via Ketone Body Signaling

D. I. Benjamin, P. I. Both, J. S. Benjamin, C. W. Nutter, J. H. Tan, J. I. Kang, L. A. Machado, J. D. D. Klein, A. d. Morree, S. I. Kim, L. I. Liu, H. Dulay, L. Feraboli, S. M. Louie, D. K. Nomura, T. A. Rando

This study shows that fasting induces a deep quiescent state in muscle stem cells through ketone body signaling, enhancing their resilience to stress.

bioRxiv · Jan 4, 2022Cell Biology