Local Monomer Levels and Established Filaments Potentiate Non-Muscle Myosin 2 Assembly
M. A. Quintanilla, H. Patel, H. Wu, K. A. Sochacki, M. Akamatsu, J. D. Rotty, F. Korobova, J. E. Bear, J. W. Taraska, P. W. Oakes, J. R. Beach
This study identifies biophysical mechanisms regulating non-muscle myosin 2 filament assembly using dynamic imaging and optogenetic tools, showing myosin monomer concentration and myosin:myosin interactions drive filament formation.
bioRxiv · Apr 26, 2023Cell Biology