Author

J. A. McLean

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. D. Sherrod· 2 shared A. C. Rutledge· 1 shared A. K. Kenworthy· 1 shared A. M. Weissmiller· 1 shared A. T. Shah· 1 shared B. F. Pfleger· 1 shared B. M. Ellis· 1 shared C. M. Adams· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioengineering

S. D. Sherrod

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Accelerating Strain Engineering using Desorption Electrospray Ionization-Imaging Mass Spectrometry and Untargeted Molecular Analysis of Intact Microbial Colonies.

B. M. Ellis, P. Babele, J. C. May, B. F. Pfleger, J. D. Young, J. A. McLean

This paper develops a DESI-IMS assay to rapidly phenotype engineered E. coli strains by analyzing their metabolomes, identifying strategies for strain optimization.

bioRxiv · Apr 1, 2021Bioengineering

A new microfluidic concept for successful in vitro culture of mouse embryos

V. Mancini, P. McKeegan, A. C. Rutledge, S. G. Condreanu, S. D. Sherrod, J. A. McLean, H. M. Picton, V. Pensabene

This paper introduces a microfluidic system for in vitro mouse embryo culture, demonstrating improved embryo development metrics compared to traditional methods.

bioRxiv · Nov 10, 2020 · PreprintBioengineering

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through interaction with Host Cell Factor-1

T. M. Popay, J. Wang, C. M. Adams, S. G. Codreanu, S. D. Sherrod, J. A. McLean, L. R. Thomas, S. L. Lorey, Y. J. Machida, A. M. Weissmiller, C. M. Eischen, Q. Liu, W. Tansey

This study identifies HCF-1 as a critical co-factor for MYC in driving mitochondrial and ribosome biogenesis gene expression, and shows its impact on cell growth and tumor progression.

bioRxiv · Jun 22, 2020Cancer Biology

Graphene nanoflakes for acute manipulation of membrane cholesterol and transmembrane signaling

K. E. Kitko, T. Hong, R. M. Lazarenko, R. J. Montenegro-Burke, A. T. Shah, Y. Zhang, K. Raghunathan, A. K. Kenworthy, M. C. Skala, J. A. McLean, Y.-Q. Xu, Q. Zhang

This study shows graphene nanoflakes manipulate membrane cholesterol, altering cell signaling in fibroblasts and neurons.

bioRxiv · Mar 18, 2019 · PreprintCell Biology