Collagen-VI expression is negatively mechanosensitive in pancreatic cancer cells and supports the metastatic niche
V. Papalazarou, J. Drew, A. Juin, H. J. Spence, C. Nixon, M. Salmeron-Sanchez, L. M. Machesky
The paper shows Collagen-VI is upregulated in pancreatic cancer cells on soft substrates and promotes metastasis by supporting the metastatic niche.
bioRxiv · Mar 3, 2022Cancer Biology