Author

J. Durgan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:clustering· 1

Frequent Co-Authors

O. Florey· 4 shared A. F. Lopez-Clavijo· 1 shared A. H. Lystad· 1 shared A. Simonsen· 1 shared A. Taubenberger· 1 shared C. V. Cannistraci· 1 shared D. G. McEwan· 1 shared D. Oxley· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersCell Biology

O. Florey

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4 papers

Recent·Most cited

Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via CASM

J. Cross, J. Durgan, D. G. McEwan, O. Florey

The paper identifies a direct ATG8 conjugation response to lysosome damage, distinct from lysophagy, involving ATG2 and lipid transfer.

bioRxiv · Mar 22, 2023 · PreprintCell Biology

V-ATPase is a universal regulator of LC3 associated phagocytosis and non-canonical autophagy

K. M. Hooper, E. Jacquin, T. Li, J. M. Goodwin, J. H. Brumell, J. Durgan, O. Florey

This study identifies V-ATPase as a universal regulator of LC3-associated phagocytosis and non-canonical autophagy, showing its role in CASM activation and its disruption by Salmonella SopF.

bioRxiv · May 20, 2021Cell Biology

De novo identification of universal cell mechanics gene signatures

M. Urbanska, Y. Ge, M. Winzi, S. Abuhattum, S. S. Ali, M. Herbig, M. Kraeter, N. Toepfner, J. Durgan, O. Florey, M. Dori, F. Calegari, F.-N. Lolo, M. A. del Pozo, A. Taubenberger, , J. Guck

This study identifies a conserved gene module involved in cell mechanics regulation using a mechanomics approach combining mechanical characterization and machine learning analysis of transcriptomic data.

bioRxiv · Apr 26, 2021Biophysics

Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine

J. Durgan, A. H. Lystad, K. Sloan, S. R. Carlsson, M. I. Wilson, E. Marcassa, R. Ulferts, J. Webster, A. F. Lopez-Clavijo, M. J. Wakelam, R. Beale, A. Simonsen, D. Oxley, O. Florey

This study shows that during non-canonical autophagy, ATG8 proteins are conjugated to phosphatidylserine instead of phosphatidylethanolamine, revealing a distinct lipidation mechanism.

bioRxiv · May 14, 2020Cell Biology