Author

V. Chandrakanthan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 6 Approach:experimental assay· 6 Research Focus:development & morphogenesis· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:imaging· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

A. Yeola· 2 shared H. Tavassoli· 2 shared J. E. Pimanda· 2 shared J. Pimanda· 2 shared P. P. Y. Chan· 2 shared P. Rorimpandey· 2 shared Y. C. Kang· 2 shared A. E. Williamson· 1 shared

Activity by Year

2019-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBioengineering

A. Yeola

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Defined microenvironments trigger in vitro gastrulation in human pluripotent stem cells

P. Srivastava, S. Romanazzo, J. Ireland, S. Nemec, T. G. Molley, P. Jayathilaka, E. Pandzic, A. Yeola, V. Chandrakanthan, J. Pimanda, K. Kilian

This study shows that microconfinement of pluripotent stem cells on hydrogels triggers gastrulation-like events without exogenous factors, leading to primitive streak formation and lineage specification.

bioRxiv · Oct 28, 2021Bioengineering

Discovery of embryonically derived bipotent endothelial-macrophage progenitor cells in postnatal aorta

A. E. Williamson, S. Liyanage, M. Hassanshahi, M. S. I. Dona, D. Toledo-Flores, D. X. A. Tran, C. Dimasi, N. Schwarz, S. Fernando, T. Salagaras, A. Long, J. Kazenwadel, N. L. Harvey, G. R. Drummond, A. Vinh, , P. J. Psaltis

The paper identifies bipotent endothelial-macrophage progenitor cells in mouse aorta that contribute to postnatal vasculogenesis and macrophage formation.

bioRxiv · Oct 18, 2021 · PreprintCell Biology

Label-free Isolation and Single Cell Biophysical Phenotyping Analysis of Primary Cardiomyocytes using Inertial Microfluidics

H. Tavassoli, P. Rorimpandey, Y. C. Kang, M. Carnell, C. Brownlee, J. Pimanda, P. P. Y. Chan, V. Chandrakanthan

This paper develops a label-free method to isolate and phenotype primary cardiomyocytes from mouse neonatal hearts using inertial microfluidics and real-time deformability cytometry.

bioRxiv · Aug 31, 2020Bioengineering

Capturing Neonatal Cardiomyocyte - Endothelial interactions on-a-Chip

H. Tavassoli, Y. C. Kang, P. Rorimpandey, J. E. Pimanda, V. Chandrakanthan, P. P. Y. Chan

This study develops a microchip system to culture neonatal cardiomyocytes and endothelial cells, revealing migratory behaviors and interactions that may inform tissue engineering and drug discovery.

bioRxiv · Aug 10, 2020 · PreprintBioengineering

Induction of Muscle Regenerative Multipotent Stem Cells from Human Adipocytes by PDGF-AB and 5-Azacytidine.

A. Yeola, S. Subramanian, R. A. Oliver, C. A. Lucas, J. A. I. Thoms, F. Yan, J. Olivier, D. Chacon, M. L. Tursky, T. Hung, C. Power, P. Hardy, D. D. Ma, J. McCarroll, M. Kavallaris, , J. E. Pimanda

This study reprograms human adipocytes into induced multipotent stem cells using PDGF-AB and 5-Azacytidine, showing their ability to regenerate tissues without ectopic growth.

bioRxiv · Jun 4, 2020Cell Biology

PDGFR alpha signaling in cardiac fibroblasts modulates quiescence, metabolism and self-renewal, and promotes anatomical and functional repair

N. S. Asli, M. Xaymardan, R. Patrick, N. Farbehi, J. Cornwell, E. Forte, A. J. Waardenberg, V. Janbandhu, S. Kesteven, V. Chandrakanthan, H. Malinowska, H. Reinhard, P. Schofield, D. Christ, I. Ahmed, , R. P. Harvey

This study investigates how PDGFR alpha signaling in cardiac fibroblasts affects quiescence, metabolism, and self-renewal, leading to improved heart repair after myocardial infarction.

bioRxiv · Jun 13, 2019 · PreprintCell Biology