Author

J. F. Hastings

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Burgess· 2 shared A. Gonzalez-Rajal· 2 shared D. N. Watkins· 2 shared D. R. Croucher· 2 shared R. A. McCloy· 2 shared V. Chin· 2 shared A. D. Murphy· 1 shared A. Nagrial· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCell Biology

A. Burgess

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Author profile →

2 papers

Recent·Most cited

A Non-Genetic, Cell Cycle Dependent Mechanism of Platinum Resistance in Lung Adenocarcinoma

A. Gonzalez-Rajal, K. Marzec, R. A. McCloy, M. Nobis, V. Chin, J. F. Hastings, K. Lai, M. Kennerson, W. E. Hughes, V. Vaghjiani, P. Timpson, J. Cain, D. N. Watkins, D. R. Croucher, A. Burgess

The paper identifies a non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma, showing that early S phase cells maintain proliferative capacity with reduced DNA damage.

bioRxiv · Nov 26, 2020 · PreprintCell Biology

Dynamic analysis of pulsed cisplatin identifies effectors of resistance in lung adenocarcinoma

J. F. Hastings, A. Gonzalez-Rajal, J. Z. Han, R. A. McCloy, Y. E. O'Donnell, M. Phimmachanh, A. D. Murphy, A. Nagrial, D. Daneshvar, V. Chin, D. N. Watkins, A. Burgess, D. R. Croucher

This study identifies P70S6K as a mediator of cisplatin resistance in lung adenocarcinoma using in vitro assays mimicking in vivo pharmacokinetics.

bioRxiv · Sep 20, 2019Cancer Biology