Author

M. Nobis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

P. Timpson· 2 shared A. Burgess· 1 shared A. C. Debruyne· 1 shared A. D. Falconer· 1 shared A. Gonzalez-Rajal· 1 shared A. Hendrix· 1 shared A. J. Lomakin· 1 shared A. P. Nikolakopoulos· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCell Biology

P. Timpson

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Author profile →

5 papers

Recent·Most cited

Live microscopy of multicellular spheroids with the multi-modal near-infrared nanoparticles reveals differences in oxygenation gradients

A. C. Debruyne, I. A. Okkelman, N. Heymans, C. Pinheiro, A. Hendrix, M. Nobis, S. M. Borisov, R. I. Dmitriev

The paper introduces multi-modal near-infrared nanoparticles for live imaging of oxygenation gradients in 3D spheroids, revealing inverted oxygenation patterns and metabolic stratification.

bioRxiv · Dec 11, 2023Cancer Biology

An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

D. Houbaert, A. P. Nikolakopoulos, O. Mece, K. Jacobs, J. Roels, G. Shankar, M. Agrawal, S. More, M. Ganne, K. Rillaerts, L. Boon, M. Swoboda, M. Nobis, L. Mourao, F. M. Bosisio, , P. Agostinis

This study shows that autophagy in lymphatic endothelial cells controls T cell egress from lymph nodes, which is critical for immune checkpoint therapy effectiveness.

bioRxiv · Jul 17, 2023Immunology

Compression-dependent microtubule reinforcement comprises a mechanostat which enables cells to navigate confined environments

R. J. Ju, A. D. Falconer, K. M. Dean, R. P. Fiolka, D. P. Sester, M. Nobis, P. Timpson, A. J. Lomakin, G. Danuser, M. D. White, D. B. Oelz, N. K. Haass, S. J. Stehbens

The paper shows that microtubules form a mechanostat to coordinate contractility and nuclear positioning during confined cell migration.

bioRxiv · Feb 8, 2022Cell Biology

A Non-Genetic, Cell Cycle Dependent Mechanism of Platinum Resistance in Lung Adenocarcinoma

A. Gonzalez-Rajal, K. Marzec, R. A. McCloy, M. Nobis, V. Chin, J. F. Hastings, K. Lai, M. Kennerson, W. E. Hughes, V. Vaghjiani, P. Timpson, J. Cain, D. N. Watkins, D. R. Croucher, A. Burgess

The paper identifies a non-genetic, cell cycle-dependent mechanism of platinum resistance in lung adenocarcinoma, showing that early S phase cells maintain proliferative capacity with reduced DNA damage.

bioRxiv · Nov 26, 2020 · PreprintCell Biology

Molecular phylogenetics and micromorphology of Australasian Stipeae (Poaceae), and the interrelation of whole-genome duplication and evolutionary radiations in this grass tribe

N. Tkach, M. Nobis, J. Schneider, H. Becher, G. Winterfeld, M. E. Barkworth, S. W. L. Jacobs, M. Roeser

The paper investigates the molecular phylogenetics and micromorphology of Austrostipa, revealing subgenus classifications, hybrid origins, and evolutionary relationships within the Stipeae tribe.

bioRxiv · Jun 5, 2020Plant Biology