Author

J. G. Markle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Approach:statistical model· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

A. Guerin· 1 shared A. R. Patterson· 1 shared A. Sugiura· 1 shared B. Bigio· 1 shared C. Bodnya· 1 shared C. Chi· 1 shared C. Deswarte· 1 shared C. Ma· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Guerin

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Functional Overlap of Inborn Errors of Immunity and Metabolism Genes Define T Cell Immunometabolic Vulnerabilities

A. R. Patterson, G. A. Needle, A. Sugiura, C. Chi, K. K. Steiner, E. L. Fisher, G. L. Robertson, C. Bodnya, J. G. Markle, V. Gama, J. C. Rathmell

The paper identifies functional overlap between inborn errors of immunity and metabolism genes, revealing immunometabolic vulnerabilities in T cells.

bioRxiv · Jan 24, 2023 · PreprintImmunology

IRF4 haploinsufficiency in a family with Whipples disease

A. Guerin, G. Kerner, N. Marr, J. G. Markle, F. Fenollar, N. Wong, S. Boughorbel, D. T. Avery, C. Ma, S. Bougarn, M. Bouaziz, V. Beziat, E. Della Mina, T. Lazarovt, L. Worley, , J.-L. Casanova

This study identifies IRF4 haploinsufficiency as the genetic cause of Whipples disease in a family, showing age-dependent incomplete penetrance and chronic Tw carriage preceding disease onset.

bioRxiv · Oct 3, 2017Immunology