A. Guerin

Dendritic cell-mediated responses to secreted Cryptosporidium effectors are required for parasite-specific CD8+ T cell responses

The paper shows that dendritic cells are essential for CD8+ T cell responses to Cryptosporidium effectors, which are secreted by the parasite.

Growth-inhibiting effects of the unconventional plant APYRASE 7 of Arabidopsis thaliana influences the LRX1/FER/RALF growth regulatory module

This study identifies APY7 as a negative regulator of cell growth in Arabidopsis, showing it modulates RALF1's growth-inhibiting effect and affects cell wall architecture and extracellular pH.

An apical membrane complex controls rhoptry exocytosis and invasion in Toxoplasma

The paper identifies CRMPs as a complex involved in rhoptry exocytosis and invasion in Toxoplasma, acting as a host-molecular sensor.

In situ structure and priming mechanism of the rhoptry secretion system in Plasmodium revealed by cryo-electron tomography

This study uses cryo-electron tomography to reveal the structure and priming mechanism of the rhoptry secretion system in Plasmodium falciparum merozoites, identifying distinct organizational states and conformational changes in the RSA.

LIX1 controls digestive mesenchyme-derived cell fate decision by regulating cristae organization in mitochondria

This study shows LIX1 regulates mitochondrial cristae organization, affecting YAP1/TAZ and KIT levels, which influences GIST cell fate and proliferation.

Live imaging of the Cryptosporidium parvum lifecycle reveals direct development of male and female gametes from type one meronts

This study uses live imaging to reveal that Cryptosporidium parvum directly develops male and female gametes from type one meronts without a distinct intermediate stage.

IRF4 haploinsufficiency in a family with Whipples disease

This study identifies IRF4 haploinsufficiency as the genetic cause of Whipples disease in a family, showing age-dependent incomplete penetrance and chronic Tw carriage preceding disease onset.