Author

J. Guitton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4 Ecology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell signaling & trafficking· 3 Research Focus:drug response / drug discovery· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2

Frequent Co-Authors

C. MACHON· 4 shared F. CATEZ· 3 shared J.-J. DIAZ· 3 shared A. VINCENT· 2 shared D. Bernard· 2 shared J. Pannequin· 2 shared N. DALLA VENEZIA· 2 shared N. MARTIN· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCancer Biology

C. MACHON

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Translational control of cell plasticity drives 5-FU tolerance

M. CHALABI-DCHAR, O. VILLERONCE, J. RIPOLL, A. VINCENT, T. FENOUIL, R. KHOUEIRY, J. KUCHARCZAK, L. JENTSCHEL, F. CATEZ, A. M. Vigneron, J. TREGUIER, C. MANDIER, C. BOUCLIER, J. VITRE, L. LAGERQVIST, , J.-J. DIAZ

The paper shows 5-FU induces translational reprogramming in colorectal cancer cells, enhancing drug tolerance through pro-tumoral gene expression and IL-8 overexpression.

bioRxiv · Jul 3, 2024 · PreprintCancer Biology

Functional precision oncology for follicular lymphoma with patient-derived xenograft in avian embryos

M. Zala, B. Lipinski, C. Costechareyre, L. Jarrosson, R. Teinturier, E. Julia, M. Lacourrege, A. Verney, J. Guitton, A. T. Glehen, E. Bachy, G. Salles, S. Huet, L. Genestier, V. Castellani, , P. Sujobert

This study develops a xenograft model in avian embryos to study follicular lymphoma response to RCHOP therapy, identifying a gene signature and validating BAX as a key effector of treatment.

bioRxiv · Jun 22, 2023 · PreprintCancer Biology

Targeting the cell and non-cell autonomous regulation of 47S synthesis by GCN2 in colon cancer.

M. Piecyk, M. Triki, P.-A. Laval, C. Duret, J. Fauvre, L. Cussonneau, C. Machon, J. Guitton, N. Rama, B. Gibert, G. Ichim, F. Catez, F. Bourdelais, S. Durand, J.-J. Diaz, , C. Chaveroux

This study shows GCN2 regulates 47S rRNA synthesis in colon cancer cells under different nutrient conditions, affecting cell survival and response to chemotherapy.

bioRxiv · Feb 8, 2023Cancer Biology

Modelling the distribution of rare and data-poor diadromous fish at sea for protected area management

S. A. M. Elliott, A. Acou, L. Beaulaton, J. Guitton, E. Reveillac, E. Rivot

The paper models the distribution of rare diadromous fish at sea using fisheries data to inform protected area management.

bioRxiv · Oct 24, 2022Ecology

Cholesterol biosynthetic pathway induces cellular senescence through ERRa

D. V. Ziegler, M. Vernier, J. Czarnecka-Herok, C. Scholtes, C. Machon, J. Guitton, J. Rieusset, V. Giguere, N. Martin, D. Bernard

This study shows the mevalonate pathway promotes cellular senescence via ERRα, causing mitochondrial dysfunction, ROS, DNA damage, and p53-dependent senescence.

bioRxiv · Oct 20, 2021Cell Biology

Are we ready to track climate-driven shifts in marine species across international boundaries? - A global survey of scientific bottom trawl data

A. A. Maureaud, R. Frelat, L. Pecuchet, N. Shackell, B. Merigot, M. L. Pinsky, K. Amador, S. C. Anderson, A. Arkhipkin, A. Auber, I. Barri, R. Bell, J. Belmaker, E. Beukhof, M. L. Camara, , Levitt-B

This study evaluates global scientific bottom trawl data to assess challenges in tracking climate-driven marine species redistributions and proposes a framework for improved data sharing and management.

bioRxiv · Jun 18, 2020Ecology

Alteration of ribosome function upon 5-fluorouracil treatment favours cancer cell drug-tolerance

G. Therizols, Z. Bash-Imam, B. Panthu, C. Machon, A. Vincent, S. Nait Slimane, M. Garcia, F. Laforets, V. Marcel, J. Boubaker-Vitre, G. Souahlia, M.-A. Albaret, H. C. Mertani, M. Prudhomme, M. Bertrand, , J.-J. Diaz

This study shows that 5-FU treatment creates fluorinated ribosomes that selectively translate survival genes, promoting drug tolerance in cancer cells.

bioRxiv · Jun 4, 2020 · PreprintCancer Biology