Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
E. Matabaro, H. Song, F. Gherlone, L. Sonderegger, A. Giltrap, S. Liver, A. Gossert, M. Künzler, J. H. Naismith
This study characterizes OphP, an enzyme that macrocyclizes multiply N-methylated peptides, revealing its unique substrate specificity and mechanism.
Chemical Science · Jan 1, 2025Peer-reviewedBiochemistry
M. Dumoux, T. Glen, E. M. L. Ho, L. M. A. Perdigao, S. Klumpe, N. B. Y. Yee, D. Farmer, J. L. R. Smith, P. Y. A. Lai, W. Bowles, R. Kelley, J. M. Plitzko, L. Wu, M. Basham, D. K. Clare, , M. Grange
This paper introduces cryo-plasma FIB/SEM for high-resolution 3D imaging of biological samples, achieving resolutions of 20-50 nm and enabling in-situ structural biology applications.
bioRxiv · Sep 21, 2022Cell Biology
C. Berger, M. Dumoux, T. Glen, N. B. y. Yee, J. M. Mitchels, Z. Patakova, J. H. Naismith, M. Grange
This paper demonstrates plasma-coupled ion sources for thinning vitrified human cells to enable pseudo-atomic structure determination in situ.
bioRxiv · Aug 1, 2022Biochemistry
C. J. Buchanan, B. Gaunt, P. J. Harrison, Y. Yang, J. Liu, A. Khan, A. M. Giltrap, A. Le Bas, P. N. Ward, K. Gupta, M. Dumoux, S. Daga, N. Picchiotti, M. Baldassarri, E. Benetti, , B. G. Davis
This paper introduces uSTA, an NMR method to analyze protein-ligand interactions, revealing SARS-CoV-2 spike binds sialoside sugars via the NTD and showing variants-of-concern lose this binding.
bioRxiv · Apr 14, 2021Biophysics
D. Zhou, H. M. E. Duyvesteyn, C.-P. Chen, C.-G. Huang, T.-H. Chen, S.-R. Shih, Y.-C. Lin, C.-Y. Cheng, S.-H. Cheng, Y.-C. Huang, T.-Y. Lin, C. Ma, J. Huo, L. Carrique, T. Malinauskas, , K.-Y. A. Huang
This paper identifies an antibody, EY6A, from a convalescent patient that neutralizes SARS-CoV-2 and cross-reacts with SARS-CoV-1 by binding a conserved epitope on the Spike protein.
bioRxiv · Jun 12, 2020Microbiology