Author

J. Hynes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

A. M. Patel· 1 shared D. Carvajal Berrio· 1 shared E. Pizzi· 1 shared G. Tian· 1 shared G. Xing· 1 shared I. A. Okkelman· 1 shared J. A. S. Roth· 1 shared J. K. Eaton· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

A. M. Patel

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The enzyme glutamate-cysteine ligase (GCL) is a target for ferroptosis induction in cancer

J. K. Eaton, P. Chatterji, L. Furst, S. Basak, A. M. Patel, Y. Y. Sweat, L. L. Cai, K. Dave, R. A. Victoria, E. Pizzi, J. Noorbakhsh, G. Tian, J. A. S. Roth, J. Hynes, G. Xing, , V. S. Viswanathan

This study identifies GCL inhibition as a strategy to induce ferroptosis in cancer cells, introducing novel inhibitors with potent cellular activity.

bioRxiv · Apr 28, 2024 · PreprintCancer Biology

Extracellular Ca2+-sensitive fluorescent protein biosensor based on a collagen-binding domain

I. A. Okkelman, R. McGarrigle, S. O' Carroll, D. Carvajal Berrio, K. Schenke-Layland, J. Hynes, R. I. Dmitriev

The paper introduces a Ca2+ biosensor based on a fluorescent protein fused with collagen-binding domains, demonstrating its use in 3D tissue models and FLIM microscopy.

bioRxiv · Mar 11, 2020Bioengineering