Author

J. J. Zulk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:ecology & biodiversity· 1

Frequent Co-Authors

K. A. Patras· 4 shared M. B. Ballard· 3 shared M. E. Mejia· 3 shared S. Ottinger· 3 shared A. W. Maresso· 2 shared J. R. Clark· 2 shared V. Mercado-Evans· 2 shared A. Flores· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersMicrobiology

K. A. Patras

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Gestational diabetes augments group B Streptococcus perinatal infection through disruptions in maternal immunity and the vaginal microbiota

V. Mercado-Evans, M. E. Mejia, J. J. Zulk, S. Ottinger, Z. Hameed, C. Serchejian, M. G. Marunde, C. M. Robertson, M. B. Ballard, N. Korotkova, A. Flores, K. A. Pennington, K. A. Patras

This study shows that gestational diabetes increases GBS perinatal infection by altering maternal immunity and vaginal microbiota, using a murine model.

bioRxiv · Jun 23, 2023Microbiology

Progress toward the development of an effective vaccine for Extraintestinal pathogenic E. coli (ExPEC): The application of the multiple-protein subunits vaccine in different murine models

Y. Xing, J. R. Clark, J. D. Chang, J. J. Zulk, D. M. Chirman, F.-A. Piedra, K. A. Patras, A. W. Maresso

This study evaluates pro-HlyA and Dual-Hit as vaccine candidates against ExPEC, showing reduced bacterial burden and increased survival in murine models.

bioRxiv · May 31, 2023 · PreprintMicrobiology

Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model

M. E. Mejia, V. Mercado-Evans, J. J. Zulk, S. Ottinger, K. Ruiz, M. B. Ballard, R. A. Britton, K. A. Patras

This study evaluates a humanized microbiota mouse model to understand how vaginal microbiota composition influences susceptibility to urogenital pathogens, finding that certain bacterial taxa correlate with reduced pathogen levels but show inconsistent in vitro and in vivo effects.

bioRxiv · Feb 9, 2023Microbiology

Phage resistance accompanies reduced fitness of uropathogenic E. coli in the urinary environment

J. J. Zulk, J. R. Clark, S. Ottinger, M. B. Ballard, M. E. Mejia, V. Mercado, E. R. Heckmann, B. C. Sanchez, B. W. Trautner, A. W. Maresso, K. A. Patras

This study shows that phage resistance in UPEC arises quickly in the urinary environment but comes with fitness costs that reduce bacterial growth and virulence.

bioRxiv · Dec 2, 2021 · PreprintMicrobiology