Author

A. Flores

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2

Frequent Co-Authors

A. C. Rowat· 1 shared A. Rawat· 1 shared A. Riestra· 1 shared A. Saeed· 1 shared B. Kain· 1 shared C. D. Rau· 1 shared C. Galvan· 1 shared C. M. Robertson· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 4 mutual co-author links

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1 shared paperCell Biology

A. C. Rowat

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma

C. Galvan, A. Flores, V. Cerillos, I. Avila, C. Murphy, W. Zheng, T. T. To, H. Christofk, W. Lowry

This study investigates metabolic flexibility in hair follicle stem cell-derived squamous cell carcinoma by blocking glycolysis and glutaminolysis, showing tumors can compensate by upregulating lactate consumption.

bioRxiv · Oct 16, 2023Cancer Biology

Gestational diabetes augments group B Streptococcus perinatal infection through disruptions in maternal immunity and the vaginal microbiota

V. Mercado-Evans, M. E. Mejia, J. J. Zulk, S. Ottinger, Z. Hameed, C. Serchejian, M. G. Marunde, C. M. Robertson, M. B. Ballard, N. Korotkova, A. Flores, K. A. Pennington, K. A. Patras

This study shows that gestational diabetes increases GBS perinatal infection by altering maternal immunity and vaginal microbiota, using a murine model.

bioRxiv · Jun 23, 2023Microbiology

Unrecognized Potent Activities of Colistin Against Clinically Important mcr+ Enterobacteriaceae Revealed in Synergy with Host Immunity

M. Kumaraswamy, A. Riestra, A. Flores, S. Uchiyama, S. Dahesh, G. Bondsater, V. Nilsson, M. Chang, H. Seo, G. Sakoulas, V. Nizet

This study reveals that colistin has previously unrecognized bactericidal activity against mcr-1+ Gram-negative bacteria in physiologic conditions and synergizes with host immunity.

bioRxiv · Mar 21, 2023Microbiology

Histone H1.0 Couples Cellular Mechanical Behaviors to Chromatin Structure

S. Hu, D. J. Chapski, N. Gehred, T. H. Kimball, T. Gromova, A. Flores, A. C. Rowat, J. J. Chen, R. R. S. Packard, E. Olszewski, J. Davis, C. D. Rau, T. A. McKinsey, M. Rosa-Garrido, T. M. Vondriska

This study shows that histone H1.0 regulates cellular mechanical behaviors by controlling chromatin structure and gene expression in response to extracellular stress.

bioRxiv · Nov 29, 2022Cell Biology

Genome mining, phylogenetic, and functional analysis of arsenic (As) resistance operons in Bacillus strains, isolated from As-rich hot spring microbial mats

A. Flores, M. F. Valencia-Marin, S. Chavez-Avila, M. I. Ramirez-Diaz, S. de los Santos Villalobos, V. Meza-Carmen, M. d. C. Orozco Mosqueda, G. Santoyo

This study identifies and characterizes arsenic resistance operons in two Bacillus strains from As-rich hot springs, showing their expression under arsenite stress and potential for bioremediation.

bioRxiv · Mar 20, 2022Microbiology

Hematopoietic stem and progenitor cells improve survival from sepsis by boosting immunomodulatory cells

D. E. Morales-Mantilla, B. Kain, D. Le, A. Flores, S. Paust, K. King

This study shows that infusing hematopoietic stem and progenitor cells (HSPCs) into septic mice improves survival by increasing immunomodulatory cells, despite similar pathogen loads.

bioRxiv · Oct 26, 2021Immunology

Virome-wide serological profiling reveals association of herpesviruses with obesity

M. R. Hasan, M. Rahman, T. Khan, A. Saeed, S. Sundararaju, A. Flores, P. Hawken, A. Rawat, N. Elkum, K. Hussain, R. Tan, P. Tang, N. Marr

This study uses ViScan to find HSV-1 and Rhinovirus A associations with obesity in Qatari adults, but not children.

bioRxiv · Sep 2, 2020Microbiology