MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas
B. Oldrini, N. Vaquero-Siguero, Q. Mu, P. Kroon, Y. Zhang, M. Galan-Ganga, Z. Bao, Z. Wang, H. Liu, J. K. Sa, J. Zhao, H. Kim, S. Rodriguez-Perales, D.-H. Nam, R. G. Verhaak, , M. Squatrito
This study shows that MGMT genomic rearrangements cause TMZ resistance in gliomas and can be detected in exosomes as potential recurrence markers.
Nature Communications · Aug 4, 2020Peer-reviewedCancer Biology