Author

J. Kuechle

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Gupta· 1 shared A. Woloszynska· 1 shared J. C. Martin· 1 shared J. Kane· 1 shared J. Ohm· 1 shared L. Gao· 1 shared M. L. Lynch· 1 shared T. J. Hagoel· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Gupta

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1 paper

Recent·Most cited

DDK inhibition disrupts replication leading to mitotic catastrophe in Ewing sarcoma

J. C. Martin, A. Gupta, T. J. Hagoel, L. Gao, M. L. Lynch, A. Woloszynska, T. Melendy, J. Kane, J. Kuechle, J. Ohm

This study shows that DDK inhibition causes replication stress and mitotic catastrophe in Ewing sarcoma cells, reducing viability and suggesting DDK as a therapeutic target.

bioRxiv · Nov 2, 2021 · PreprintCancer Biology