Author

D. C. Nguyen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

F. E.-H. Lee· 5 shared I. Sanz· 4 shared C. Saney· 2 shared J. Andrews· 2 shared M. Cabrera-Mora· 2 shared S. Lonial· 2 shared A. Derrico· 1 shared A. Diouf· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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5 shared papersImmunology

F. E.-H. Lee

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Author profile →

6 papers

Recent·Most cited

Synergistic Effects of Sulopenem in Combination with Cefuroxime or Durlobactam against Mycobacterium abscessus

K. M. Dousa, E. Shin, S. G. Kurz, M. Plummer, M. Nantongo, C. R. Bethel, M. A. Taracila, D. C. Nguyen, B. N. Kreiswith, C. L. Daley, K. E. Remy, S. Holland, R. A. Bonomo

This study shows that sulopenem combined with cefuroxime or durlobactam synergistically inhibits Mycobacterium abscessus, with BLIs enhancing antibacterial effects.

bioRxiv · Dec 15, 2023 · PreprintMicrobiology

Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5

L. T. Wang, A. J. R. Cooper, B. Farrell, K. Miura, A. Diouf, N. Muller-Sienerth, C. Crosnier, L. Purser, M. Maciuszek, J. R. Barrett, K. McHugh, C. Tucker, S. Li, S. Doumbo, D. Doumtabe, , J. Tan

The paper identifies potent neutralizing antibodies against the malaria antigen RH5 from natural infection, showing they target similar epitopes as vaccine-induced antibodies.

bioRxiv · Oct 4, 2023Immunology

Majority of human circulating plasmablasts stop blasting: A probable misnomer

D. C. Nguyen, C. Saney, I. T. Hentenaar, M. Cabrera-Mora, M. C. Woodruff, J. Andrews, S. Lonial, I. Sanz, F. E.-H. Lee

The study shows most blood plasmablasts are not actively dividing, suggesting the term 'plasmablast' may be misleading.

bioRxiv · Sep 10, 2023 · PreprintImmunology

Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses

M. Duan, D. C. Nguyen, C. J. Joyner, C. Saney, C. Tipton, J. Andrews, S. Lonial, C. Kim, I. Hentenaar, A. Kosters, E. Ghosn, A. Jackson, S. Knechtle, S. Maruthamuthu, S. Chandran, , F. E.-H. Lee

The study maps human bone marrow plasma cell heterogeneity using single-cell transcriptomics, revealing maturation pathways and molecular features of long-lived plasma cells.

bioRxiv · Jan 18, 2023 · PreprintImmunology

Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection

N. S. Haddad, D. C. Nguyen, M. E. Kuruvilla, A. Morrison-Porter, F. Anam, K. S. Cashman, R. P. Ramonell, S. Kyu, A. S. Saini, M. Cabrera-Mora, A. Derrico, D. Alter, J. D. Roback, M. Horwath, J. B. O'Keefe, , F. E.-H. Lee

This paper develops a multiplex immunoassay to measure SARS-CoV-2 antibody responses and finds that severe COVID-19 is associated with higher early antibody levels against S1 and N proteins.

bioRxiv · Dec 4, 2020 · PreprintImmunology

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

S. J. Zost, P. Gilchuk, R. Chen, J. B. Case, J. X. Reidy, A. Trivette, R. S. Nargi, R. E. Sutton, N. Suryadevara, E. C. Chen, E. Binshtein, S. Shrihari, M. A. Ostrowski, H. Y. Chu, J. E. Didier, , J. E. Crowe

This study isolates and profiles human monoclonal antibodies against SARS-CoV-2 spike protein, identifying neutralizing antibodies targeting the receptor-binding domain.

bioRxiv · May 12, 2020Immunology