Author

S. M. Barratt-Boyes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. Kim· 2 shared A. M. Berezuk· 2 shared B. R. Treat· 2 shared D. Mannar· 2 shared J. L. Jacobs· 2 shared J. W. Mellors· 2 shared J. W. Saville· 2 shared M. D. Sobolewski· 2 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Kim

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains

C. Chen, J. W. Saville, M. M. Marti, A. Schaefer, M. H. Cheng, D. Mannar, X. Zhu, A. M. Berezuk, A. Banerjee, M. D. Sobolewski, A. Kim, B. R. Treat, P. M. Da Silva Castanha, N. Enick, K. D. McCormick, , W. Li

This study identifies a biparatopic VH domain that neutralizes SARS-CoV-2 VOCs, including Omicron, with high potency in vitro and in a mouse model.

bioRxiv · Feb 18, 2022 · PreprintImmunology

Emerging SARS-CoV-2 Variants of Concern: Spike Protein Mutational Analysis and Epitope for Broad Neutralization

D. Mannar, J. W. Saville, Z. Sun, X. Zhu, M. M. Marti, S. S. Srivastava, A. M. Berezuk, S. Zhou, K. Tuttle, M. D. Sobolewski, A. Kim, B. R. Treat, P. Mayrelle Da Silva Castanha, J. L. Jacobs, S. M. Barratt-Boyes, , S. Subramaniam

This study identifies a broadly neutralizing antibody fragment and analyzes spike protein mutations in SARS-CoV-2 variants to understand their structural and functional impacts on antibody evasion.

bioRxiv · Dec 17, 2021Biochemistry

TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques

A. A. Upadhyay, T. N. Hoang, M. Pino, A. K. Boddapati, E. G. Viox, M. Y. H. Lee, J. Corry, Z. Strongin, D. A. Cowan, E. N. Beagle, T. R. Horton, S. Hamilton, H. Aoued, J. L. Harper, K. Nguyen, , S. E. Bosinger

This study identifies two macrophage populations driving inflammation in the lower airway during SARS-CoV-2 infection in rhesus macaques and shows baricitinib effectively reduces their influx and cytokine production.

bioRxiv · Oct 5, 2021 · PreprintMicrobiology