Author

J. M. Belardinelli

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Jackson· 2 shared A. G. Coyne· 1 shared A. J. Whitehouse· 1 shared B. Javid· 1 shared C. Abell· 1 shared C. Toniolo· 1 shared G. E. Fantner· 1 shared H. A. Eskandarian· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

M. Jackson

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2 papers

Recent·Most cited

Mechanical morphotype switching as an adaptive response in mycobacteria

H. A. Eskandarian, Y.-X. Chen, C. Toniolo, J. M. Belardinelli, Z. Palcekova, P. D. Ashby, G. E. Fantner, M. Jackson, J. D. McKinney, B. Javid

The paper shows mycobacteria change their cell surface stiffness to survive macrophage stress, using mechanical morphotype switching as an adaptive strategy.

bioRxiv · Apr 6, 2022Microbiology

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification

S. E. Thomas, A. J. Whitehouse, K. Brown, J. M. Belardinelli, R. Lahiri, M. D. J. Libardo, P. Gupta, S. Malhotra, H. I. M. Boshoff, M. Jackson, C. Abell, A. G. Coyne, T. L. Blundell, R. A. Floto, V. Mendes

This study identifies new TrmD inhibitors for mycobacterial infections using fragment-based drug discovery, showing activity against multiple mycobacterial species in vitro and in macrophage models.

bioRxiv · May 19, 2019Biochemistry