Author

J. M. Burchell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

R. Beatson· 2 shared C. E. Gillett· 1 shared C. Gillett· 1 shared D. Choy· 1 shared D. Cozzetto· 1 shared D. R. Withers· 1 shared D. Sosnowska· 1 shared E. Pfeifer· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

R. Beatson

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Author profile →

2 papers

Recent·Most cited

Perivascular macrophages collaborate to facilitate chemotherapy resistance in cancer

J. E. Anstee, J. W. Opzoomer, I. Dean, H. P. Muller, M. Bahri, K. Liakath-Ali, Z. Liu, D. Choy, J. Caron, D. Sosnowska, R. Beatson, T. Muliaditan, Z. An, C. E. Gillett, G. Lan, , J. N. Arnold

This study identifies Lyve-1+ perivascular macrophages that form nests and contribute to chemotherapy resistance by excluding CD8+ T-cells and relying on IL-6 and CCR5/CCL3/4 signaling.

bioRxiv · Feb 3, 2022Cancer Biology

Cancer-associated hypersialylated MUC1 drives the differentiation of monocytes into macrophages with a pathogenic phenotype

R. Beatson, R. Graham, F. Grundland Freile, D. Cozzetto, S. Kannambath, E. Pfeifer, N. Woodman, J. Owen, R. Nuamah, U. Mandel, S. Pinder, C. Gillett, T. Noll, I. Bouybayoune, J. Taylor-Papadimitriou, J. M. Burchell

This study identifies MUC1-ST as a driver of monocyte differentiation into pathogenic macrophages in the tumor microenvironment, associated with poor breast cancer prognosis.

bioRxiv · May 6, 2020Cancer Biology