Author

J. Caron

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Approach:wet-lab / biochemical assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

D. R. Withers· 2 shared D. Sosnowska· 2 shared I. Dean· 2 shared J. E. Anstee· 2 shared J. N. Arnold· 2 shared J. W. Opzoomer· 2 shared S. Kordasti· 2 shared T. Lawrence· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

D. R. Withers

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Author profile →

3 papers

Recent·Most cited

Notch Signaling in regulating Bone-derived Nanoparticles (BNPs) enhanced Osteogenic Differentiation

S. Wang, B. Wang, A. Stellpflug, J. Caron, S. Fasciano

This study investigates how bone-derived nanoparticles (BNPs) enhance osteogenic differentiation of mesenchymal stem cells (MSCs) through Notch signaling, specifically by increasing Dll4 expression.

bioRxiv · Jun 19, 2024 · PreprintBioengineering

Perivascular macrophages collaborate to facilitate chemotherapy resistance in cancer

J. E. Anstee, J. W. Opzoomer, I. Dean, H. P. Muller, M. Bahri, K. Liakath-Ali, Z. Liu, D. Choy, J. Caron, D. Sosnowska, R. Beatson, T. Muliaditan, Z. An, C. E. Gillett, G. Lan, , J. N. Arnold

This study identifies Lyve-1+ perivascular macrophages that form nests and contribute to chemotherapy resistance by excluding CD8+ T-cells and relying on IL-6 and CCR5/CCL3/4 signaling.

bioRxiv · Feb 3, 2022Cancer Biology

Macrophages orchestrate the expansion of a pro-angiogenic perivascular niche during cancer progression

J. W. Opzoomer, J. E. Anstee, I. Dean, E. J. Hill, I. Bouybayoune, J. Caron, T. Muliaditan, P. Gordon, D. Sosnowska, R. Nuamah, S. E. Pinder, T. Ng, F. Dazzi, S. Kordasti, D. R. Withers, , J. N. Arnold

This study identifies Lyve-1+ tumor-associated macrophages that support tumor growth by maintaining a pro-angiogenic perivascular niche through platelet-derived growth factor-CC-dependent expansion of mesenchymal cells.

bioRxiv · Oct 30, 2020Cancer Biology