Author

J. N. Arnold

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell-cell communication· 2 Organism:human· 2

Frequent Co-Authors

D. R. Withers· 2 shared D. Sosnowska· 2 shared I. Dean· 2 shared J. Caron· 2 shared J. E. Anstee· 2 shared J. W. Opzoomer· 2 shared S. Kordasti· 2 shared T. Lawrence· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

D. R. Withers

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Author profile →

4 papers

Recent·Most cited

Human TUBA1B short open reading frame product regulates cancer cell growth via importin-β

Y. Tao, X. Bai, Y. Zhou, Y. Zhao, L. Yang, S. Zhang, H. Liu, X. Huang, E. Schneider, A. Zampetaki, A. Margariti, M. Giacca, J. N. Arnold, L. Zeng, T. Cai

This study identifies TUBA1B-sORF1, a novel protein from the TUBA1B gene, which promotes cancer cell growth by facilitating nuclear translocation of β-catenin.

bioRxiv · Aug 26, 2023 · PreprintCancer Biology

Heme oxygenase-1 expressing omental macrophages as a therapeutic target in ovarian high grade serous carcinoma

S. Spear, O. Le Saux, H. B. Mirza, K. Tyson, J. Bickel, F. Grundland Freile, A. P. Siskos, C. Balcells, J. B. Walton, C. Woodman, D. P. Ennis, N. Iyer, C. Aguirre Hernandez, Y. Xu, P. Spiliopoulou, , I. A. McNeish

This study identifies HMOX1-expressing omental macrophages as a therapeutic target and biomarker for poor prognosis ovarian high-grade serous carcinoma.

bioRxiv · Jul 18, 2023 · PreprintCancer Biology

Perivascular macrophages collaborate to facilitate chemotherapy resistance in cancer

J. E. Anstee, J. W. Opzoomer, I. Dean, H. P. Muller, M. Bahri, K. Liakath-Ali, Z. Liu, D. Choy, J. Caron, D. Sosnowska, R. Beatson, T. Muliaditan, Z. An, C. E. Gillett, G. Lan, , J. N. Arnold

This study identifies Lyve-1+ perivascular macrophages that form nests and contribute to chemotherapy resistance by excluding CD8+ T-cells and relying on IL-6 and CCR5/CCL3/4 signaling.

bioRxiv · Feb 3, 2022Cancer Biology

Macrophages orchestrate the expansion of a pro-angiogenic perivascular niche during cancer progression

J. W. Opzoomer, J. E. Anstee, I. Dean, E. J. Hill, I. Bouybayoune, J. Caron, T. Muliaditan, P. Gordon, D. Sosnowska, R. Nuamah, S. E. Pinder, T. Ng, F. Dazzi, S. Kordasti, D. R. Withers, , J. N. Arnold

This study identifies Lyve-1+ tumor-associated macrophages that support tumor growth by maintaining a pro-angiogenic perivascular niche through platelet-derived growth factor-CC-dependent expansion of mesenchymal cells.

bioRxiv · Oct 30, 2020Cancer Biology