Author

J. M. Nerbonne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Physiology· 2

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:electrophysiology· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

A. Lesage· 2 shared C. Marionneau· 2 shared D. Maloney· 2 shared J. Silva· 2 shared M. Lorenzini· 2 shared R. R. Townsend· 2 shared S. Burel· 2 shared W. Wang· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPhysiology

A. Lesage

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

FHF2 phosphorylation and regulation of native myocardial NaV1.5 channels

A. Lesage, M. Lorenzini, S. Burel, M. Sarlandie, F. Bibault, D. Maloney, J. Silva, R. R. Townsend, J. M. Nerbonne, C. Marionneau

This study identifies phosphorylation sites on FHF2 in mouse NaV1.5 channels and shows differential regulation of neonatal and adult ventricular NaV1.5 by FHF2 phosphorylation.

bioRxiv · Jan 31, 2023Physiology

Identification of Structures for Ion Channel Kinetic Models

K. E. Mangold, W. Wang, E. K. Johnson, D. Bhagavan, J. D. Moreno, J. M. Nerbonne, J. Silva

The paper presents a method to identify Markov model topologies for ion channel dynamics using experimental data from two types of voltage-gated ion channels.

bioRxiv · Apr 6, 2021Biophysics

Mechanical dysfunction induced by a hypertrophic cardiomyopathy mutation is the primary driver of cellular adaptation

S. R. Clippinger, P. E. Cloonan, W. Wang, L. Greenberg, W. T. Stump, P. Angsutararux, J. M. Nerbonne, M. J. Greenberg

This study shows that a HCM mutation causes mechanical dysfunction, which drives cellular adaptation through altered force generation and signaling pathways.

bioRxiv · May 4, 2020Biophysics

Proteomic and functional mapping of cardiac NaV1.5 channel phosphorylation reveals multisite regulation of surface expression and gating

M. Lorenzini, S. Burel, A. Lesage, E. Wagner, C. Charriere, P.-M. Chevillard, B. Evrard, D. Maloney, K. M. Ruff, R. V. Pappu, S. Wagner, J. M. Nerbonne, J. R. Silva, R. R. Townsend, L. S. Maier, C. Marionneau

The paper identifies 42 phosphorylation sites on NaV1.5 channels in mouse hearts and shows their roles in regulating channel expression and gating.

bioRxiv · Apr 29, 2020Physiology