Author

A. J. Auguste

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:cryo-EM· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

W. B. Stone· 3 shared C. Pueblas Castro· 2 shared D. E. Alvarez· 2 shared E. F. Castro· 2 shared J. Cassataro· 2 shared K. A. Pasquevich· 2 shared L. A. Bruno· 2 shared L. M. Coria· 2 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersImmunology

W. B. Stone

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nanobodies against SARS-CoV-2 reduced virus load in the brain of challenged mice and neutralized Wuhan, Delta and Omicron Variants

M. F. Pavan, M. Bok, R. Betanzos San Juan, J. P. Malito, G. A. Marcoppido, D. R. Franco, D. A. Militello, J. M. Schammas, S. Bari, W. B. Stone, K. Lopez, D. Porier, J. Muller, A. J. Auguste, L. Yuan, , L. I. Ibanez

This study develops nanobodies against SARS-CoV-2 that neutralize multiple variants and reduce viral load in the brain of infected mice.

bioRxiv · Mar 14, 2023 · PreprintImmunology

Humoral and T-cell-mediated responses to a pre-clinical Zika vaccine candidate that utilizes a unique insect-specific flavivirus platform

D. L. Porier, A. Adam, L. Kang, P. Michalak, J. Tupik, M. A. Santos, C. Lee, I. C. Allen, T. Wang, A. J. Auguste

This study evaluates immune responses to an ISFV-based Zika vaccine, showing neutralizing antibodies and T-cells contribute to protection.

bioRxiv · Mar 1, 2023 · PreprintMicrobiology

A Gamma-adapted recombinant subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection.

L. M. Coria, J. M. Rodriguez, A. Demaria, L. A. Bruno, M. Rios Medrano, C. Pueblas Castro, E. F. Castro, S. A. Del Priore, A. C. Hernando Insua, I. G. Kaufmann, L. M. Saposnik, W. B. Stone, L. Prado, V. Krum, F. M. Zurvarra, , J. Cassataro

This paper develops a Gamma-adapted subunit vaccine that induces broad neutralizing antibodies and protects mice against SARS-CoV-2 variants, including Omicron.

bioRxiv · Jan 3, 2023Immunology

A novel bacterial protease inhibitor adjuvant in RBD-based COVID-19 vaccine formulations increases neutralizing antibodies, specific germinal center B cells and confers protection against SARS-CoV-2 infection.

L. M. Coria, L. M. Saposnik, C. Pueblas Castro, E. F. Castro, L. A. Bruno, W. B. Stone, P. S. Perez, M. L. Darriba, L. B. Chemes, J. Alcain, I. Mazzitelli, A. Varese, M. Salvatori, A. J. Auguste, D. E. Alvarez, , J. Cassataro

This paper evaluates RBD-based vaccine formulations with different adjuvants, finding that U-Omp19+Alum significantly increases neutralizing antibodies, B cells, and provides protection against SARS-CoV-2.

bioRxiv · Dec 7, 2021 · PreprintImmunology

Near-atomic resolution Cryo-EM structure of Mayaro virus identifies key structural determinants of alphavirus particle formation

D. Chmielewski, J. Kaelber, J. Jin, S. C. Weaver, A. J. Auguste, W. Chiu

The paper presents a near-atomic resolution cryo-EM structure of Mayaro virus, revealing structural determinants of alphavirus particle formation and identifying key residues involved in assembly.

bioRxiv · Jan 14, 2021 · PreprintMicrobiology