Author

J. M. Taft

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Organism:virus· 1

Frequent Co-Authors

S. T. Reddy· 3 shared C. R. Weber· 2 shared L. Frei· 2 shared A. G. Lujan Hernandez· 1 shared A. Iwasaki· 1 shared A. Kummer· 1 shared A. Sato· 1 shared B. E. Correia· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

S. T. Reddy

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3 papers

Recent·Most cited

Deep learning-guided selection of antibody therapies with enhanced resistance to current and prospective SARS-CoV-2 Omicron variants

L. Frei, B. Gao, J. Han, J. M. Taft, E. B. Irvine, C. R. Weber, R. Kumar, B. Eisinger, S. T. Reddy

This study uses deep learning to identify antibodies resistant to SARS-CoV-2 Omicron variants by predicting their binding and escape from mutations.

bioRxiv · Oct 9, 2023 · PreprintImmunology

A synthetic bispecific antibody capable of neutralizing SARS-CoV-2 Delta and Omicron

T. Z. Yuan, C. Lucas, V. S. Monteiro, A. Iwasaki, M. L. Yang, H. F. Nepita, A. G. Lujan Hernandez, J. M. Taft, L. Frei, S. T. Reddy, C. Weber, K. P. Malobisky, R. Mesquita, A. Sato

This paper describes a synthetic bispecific antibody that neutralizes SARS-CoV-2 Delta and Omicron variants with picomolar affinity.

bioRxiv · Jan 4, 2022 · PreprintImmunology

The Physiological Landscape and Specificity of Antibody Repertoires

L. Csepregi, K. B. Hoehn, D. Neumeier, J. M. Taft, S. Friedensohn, C. R. Weber, A. Kummer, F. Sesterhenn, B. E. Correia, S. T. Reddy

This study analyzes antibody repertoires across multiple lymphoid organs in immunized mice, finding that strong humoral responses lead to consolidated, overlapping B-cell clones and a uniform but redundant physiological landscape.

bioRxiv · Sep 15, 2021 · PreprintImmunology