Author

J. Madzo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. Jelinek· 2 shared K. Keith· 2 shared S. Maegawa· 2 shared A. Bellacosa· 1 shared A. Kossenkov· 1 shared A. Sun· 1 shared B. Gewurz· 1 shared C. Jobin· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

J. Jelinek

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ZNF251 haploinsufficiency confers PARP inhibitors resistance in BRCA1-mutated cancer cells through activation of homologous recombination

H. Li, S. Chatla, X. Liu, Z. Tian, U. Vekariya, P. Wang, D. Kim, S. Octaviani, Z. Lian, G. Morton, Z. Feng, D. Yang, K. Sullivan-Reed, W. Childers, X. Yu, , J. Huang

This study identifies ZNF251 haploinsufficiency as a mechanism conferring PARP inhibitor resistance in BRCA1-mutated cancer cells through RAD51-mediated homologous recombination.

bioRxiv · Sep 29, 2022 · PreprintCancer Biology

The Nuclear Lamina binds the EBV genome during latency and regulates viral gene expression

L. B. Caruso, R. Guo, K. Keith, J. Madzo, D. Maestri, S. Boyle, J. Wasserman, A. Kossenkov, B. Gewurz, I. Tempera

bioRxiv · Aug 5, 2021Microbiology

Microbiota Accelerates Age-Related CpG island Methylation in Colonic Mucosa

A. Sun, L. Cole, S. Maegawa, P. H. Park, K. Keith, J. Madzo, J. Jelinek, C. Jobin, J.-P. J. Issa

The paper shows microbiota accelerates age-related CpG island methylation in colonic mucosa, similar to cancer, and interacts with inflammation to enhance methylation changes.

bioRxiv · Aug 28, 2020 · PreprintMicrobiology

TET1 and TDG suppress intestinal tumorigenesis by down regulating the inflammatory and immune response pathways

R. Tricarico, J. Madzo, G. Scher, S. Maegawa, J. Jelinek, C. Scher, W.-C. Chang, E. Nicolas, Y. Zhou, M. Slifker, K. Devarajan, K. Q. Cai, P. Nakajima, J. Xu, P. Mancuso, , A. Bellacosa

This study shows that TET1 and TDG reduce intestinal tumor formation by suppressing inflammatory and immune response pathways through DNA demethylation.

bioRxiv · Jun 21, 2019 · PreprintCancer Biology