Author

K. Johann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 4 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Assay:proteomics· 4 Research Focus:cell type annotation· 3 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Research Focus:differential expression· 1 Assay:electrophysiology· 1

Frequent Co-Authors

M. Kleinert· 3 shared A. M. Fritzen· 2 shared C. Clemmensen· 2 shared C. Gil· 2 shared A. Artati· 1 shared A. B. Klein· 1 shared A. Best· 1 shared A. Cebrian-Serrano· 1 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersPhysiology

M. Kleinert

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy in mice lacking thyroid hormone receptor beta

R. Dore, S. C. Sentis, K. Johann, N. Lopez-Alcantara, J. Resch, L. C. Moeller, D. Fuehrer, B. Obermayer-Wasserscheid, R. Opitz, J. Mittag

This study shows that TR{beta}-KO mice exhibit partial resistance to thyroid hormone-induced tachycardia and cardiac hypertrophy when studied at thermoneutrality.

bioRxiv · Nov 21, 2023Physiology

Pantothenate Kinase 4 controls efficient skeletal muscle energy substrate metabolism via acetyl-CoA

A. Miranda-Cervantes, A. M. Fritzen, S. H. Raun, O. Hodek, L. L. V. Moller, K. Johann, L. Deisen, P. Gregorevic, A. Gudiksen, A. Artati, J. Adamski, N. R. Andersen, P. Schjerling, A. Cebrian-Serrano, M. Jaehnert, , M. Kleinert

This study identifies PanK4 as a regulator of skeletal muscle energy metabolism, showing its role in acetyl-CoA regulation and metabolic flexibility.

bioRxiv · Aug 14, 2023 · PreprintPhysiology

Cross-species comparison of pregnancy-induced GDF15

A. Klein, P. Ranea-Robles, T. Nicolaisen, C. Gil, K. Johann, J. Quesada, N. Pistolevij, K. Hviid, L. Olsen, S. Offersen, J. Helge, H. Svarre-Nielsen, J. Bakker, M. Kleinert, C. Clemmensen

This study compares GDF15 expression during pregnancy across species, finding significant differences in plasma levels and expression between humans/macacaques and rodents.

bioRxiv · Jun 19, 2023Physiology

{Pi}-{Pi} Interactions Stabilize PeptoMicelle-Based Formulations of Pretomanid Derivatives Leading to Promising Therapy Against Tuberculosis in Zebrafish and Mouse Models

N.-J. K. Dal, G. Schafer, A. M. Thompson, S. Schmitt, N. Redinger, N. Alonso-Rodriguez, K. Johann, J. Ojong, J. Wohlmann, A. Best, K. Koynov, R. Zentel, U. E. Shaible, G. Griffiths, M. Barz, F. Fenaroli

This paper develops PeptoMicelle-based formulations of pretomanid derivatives using π-π interactions, showing improved efficacy against tuberculosis in zebrafish and mouse models.

bioRxiv · Mar 10, 2022Bioengineering

The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance

A. B. Klein, T. S. Nicolaisen, K. Johann, A. M. Fritzen, C. V. Mathiesen, C. Gil, N. S. Pilmark, K. Karstoft, M. B. Blond, J. S. Quist, R. J. Seeley, K. Faerch, J. Lund, M. Kleinert, C. Clemmensen

This study shows metformin increases GDF15 but does not rely on the GDF15-GFRAL pathway for its weight-lowering effects in mice.

bioRxiv · Feb 16, 2022Physiology